Januvia and Daliresp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Daliresp (roflumilast). Common drug interactions include cardiac arrest among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Januvia and Daliresp. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

What is Daliresp?

Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.



On Jul, 14, 2026

59 people who take Januvia and Daliresp together, and have interactions are studied.

Januvia and Daliresp drug interactions.

What are the common drug interactions of Januvia and Daliresp, by gender? *:

female:

  1. Cardiac arrest
  2. Cardiac disorder
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Depression
  5. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  6. Emotional disorder
  7. Feeling hot
  8. Flushing (the warm, red condition of human skin)
  9. Hallucination (an experience involving the perception of something not present)
  10. Headache (pain in head)

male:

  1. Weight decreased
  2. Death
  3. Diarrhoea
  4. Dizziness
  5. Feeling jittery
  6. Haemoglobin decreased
  7. Heart rate increased
  8. Palpitations (feelings or sensations that your heart is pounding or racing)
  9. Peripheral swelling
  10. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

What are the common drug interactions of Januvia and Daliresp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Depression
  2. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  3. Fear
  4. Hallucination (an experience involving the perception of something not present)
  5. Suicidal ideation

50-59:

  1. Weight decreased
  2. Pneumonia
  3. Infection
  4. Arthralgia (joint pain)
  5. Back pain
  6. Blood glucose increased
  7. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  8. Cough
  9. Diarrhoea
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fatigue (feeling of tiredness)
  3. Abdominal distension
  4. Adverse event
  5. Anaemia (lack of blood)
  6. Cardiac failure congestive
  7. Decreased appetite
  8. Diarrhoea
  9. Dizziness
  10. Haemoglobin decreased

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 28.81%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 16 people, 27.12%
  3. Multiple Myeloma (cancer of the plasma cells): 9 people, 15.25%
  4. Pain: 5 people, 8.47%
  5. High Blood Pressure: 5 people, 8.47%
  6. Type 2 Diabetes: 4 people, 6.78%
  7. Stress And Anxiety: 4 people, 6.78%
  8. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 6.78%
  9. High Blood Cholesterol: 4 people, 6.78%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Januvia and Daliresp?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Januvia and Daliresp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Januvia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Daliresp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Januvia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daliresp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sitagliptin phosphate and roflumilast (the active ingredients of Januvia and Daliresp, respectively), and Januvia and Daliresp (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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