Januvia and Peridex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Peridex (chlorhexidine gluconate). Common drug interactions include diverticulum intestinal among females and abscess limb among males.

The phase IV clinical study analyzes what interactions people have when they take Januvia and Peridex. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

On Aug, 12, 2026

17 people who take Januvia and Peridex together, and have interactions are studied.

What are the common drug interactions of Januvia and Peridex, by gender? *:

female:

Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Bone loss
Cardiomegaly (increased size of heart than normal)
Emotional distress
Gingival bleeding (bleeding gums)
Gingival erosion (gum ulcer)
Gout (uric acid crystals building up in the body)
Impaired healing
Loose tooth
Nephrolithiasis (calculi in the kidneys)

male:

Abscess limb (limb infection)
Chronic kidney disease
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Hypervolaemia (abnormally increased volume of blood)
Post-traumatic stress disorder

What are the common drug interactions of Januvia and Peridex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Abscess limb (limb infection)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Hypervolaemia (abnormally increased volume of blood)
Post-traumatic stress disorder

60+:

Bone loss
Cardiomegaly (increased size of heart than normal)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Osteonecrosis of jaw (death of bone of jaw)
Ovarian cyst (fluid filled sac of the ovary)
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Quality of life decreased
Road traffic accident
Tooth loss

What are the existing conditions these people have? *

Pain: 8 people, 47.06%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 35.29%
Type 2 Diabetes: 5 people, 29.41%
Infection: 4 people, 23.53%
Metastases To Bone (cancer spreads to bone): 4 people, 23.53%
Hypotension (abnormally low blood pressure): 3 people, 17.65%
Weight Decreased: 2 people, 11.76%
Blood Pressure Abnormal: 2 people, 11.76%
Constipation: 2 people, 11.76%
Depression: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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