Januvia and Prasugrel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Prasugrel (prasugrel). Common drug interactions include hospitalisation among females and depressed mood among males.
The phase IV clinical study analyzes what interactions people have when they take Januvia and Prasugrel. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Januvia?
Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.
What is Prasugrel?
Prasugrel has active ingredients of prasugrel. eHealthMe is studying from 1,193 Prasugrel users. Check the latest studies of Prasugrel.
13 people who take Januvia and Prasugrel together, and have interactions are studied.
What are the common drug interactions of Januvia and Prasugrel, by gender? *:
female:
- Hospitalisation
male:
- Depressed mood
- White blood cell count increased
- Cardiovascular disorder (heart diseases)
- Chest pain
- Chronic kidney disease
- Contusion (a type of hematoma of tissue in which capillaries)
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Coronary artery stenosis (narrowing of coronary artery)
- Death
- Device occlusion
What are the common drug interactions of Januvia and Prasugrel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
60+:
- Depressed mood
- Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
- Chest pain
- Contusion (a type of hematoma of tissue in which capillaries)
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Coronary artery stenosis (narrowing of coronary artery)
- Death
- Device occlusion
- Diarrhoea
- Dizziness
What are the existing conditions these people have? *
- Depression: 3 people, 23.08%
- Heart Attack: 2 people, 15.38%
- High Blood Pressure: 2 people, 15.38%
- Infection: 2 people, 15.38%
- High Blood Cholesterol: 2 people, 15.38%
- Stress And Anxiety: 2 people, 15.38%
- Insomnia (sleeplessness): 2 people, 15.38%
- Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 15.38%
- Cardiac Disorder: 2 people, 15.38%
- Nausea (feeling of having an urge to vomit): 2 people, 15.38%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Januvia and Prasugrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Januvia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Prasugrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Januvia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prasugrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sitagliptin phosphate and prasugrel (the active ingredients of Januvia and Prasugrel, respectively), and Januvia and Prasugrel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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