Januvia and Ribasphere drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Ribasphere (ribavirin). Common drug interactions include fatigue among females and dizziness among males.
The phase IV clinical study analyzes what interactions people have when they take Januvia and Ribasphere. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Januvia?
Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.
What is Ribasphere?
Ribasphere has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 9,336 Ribasphere users. Check the latest studies of Ribasphere.
21 people who take Januvia and Ribasphere together, and have interactions are studied.

What are the common drug interactions of Januvia and Ribasphere, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Rash
- Dizziness
- Diarrhoea
- Haemoglobin decreased
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Blood glucose increased
- Chest discomfort
male:
- Dizziness
- Hypersensitivity
- Epistaxis (bleed from the nose)
- Fatigue (feeling of tiredness)
- Joint swelling
- Memory impairment
- Muscle spasms (muscle contraction)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Nasal dryness (dry nose)
- Psychomotor hyperactivity (feelings of extreme restlessness)
What are the common drug interactions of Januvia and Ribasphere, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Burning sensation
- Confusional state
- Dizziness
- Memory impairment
- Muscle spasms (muscle contraction)
- Psychomotor hyperactivity (feelings of extreme restlessness)
- Rash
- Vomiting
50-59:
- Rash
- Joint swelling
- Arthralgia (joint pain)
- Chest discomfort
- Chills (felling of cold)
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Decreased appetite
- Haemolytic anaemia (anaemia due to haemolysis)
- Blood uric acid increased
- Neck pain
60+:
- Hypersensitivity
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
- Swollen tongue (swelling of tongue)
What are the existing conditions these people have? *
- High Blood Pressure: 4 people, 19.05%
- Type 2 Diabetes: 3 people, 14.29%
- Urination - Painful: 2 people, 9.52%
- Thyroid Diseases: 2 people, 9.52%
- Prostate Cancer: 2 people, 9.52%
- Back Pain: 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Januvia and Ribasphere?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Januvia (72,818 reports)
- Ribasphere (9,336 reports)
Browse all drug interactions of Januvia and Ribasphere:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Januvia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ribasphere:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Januvia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ribasphere and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
- Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on sitagliptin phosphate and ribavirin (the active ingredients of Januvia and Ribasphere, respectively), and Januvia and Ribasphere (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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