Jardiance and Testosterone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Jardiance (empagliflozin) and Testosterone (testosterone). Common drug interactions include headache among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Jardiance and Testosterone. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Jardiance?

Jardiance has active ingredients of empagliflozin. It is often used in hyperglycemia. eHealthMe is studying from 44,460 Jardiance users. Check the latest studies of Jardiance.

What is Testosterone?

Testosterone has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 6,457 Testosterone users. Check the latest studies of Testosterone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

55 people who take Jardiance and Testosterone together, and have interactions are studied.

Jardiance and Testosterone drug interactions.

What are the common drug interactions of Jardiance and Testosterone, by gender? *:

female:

  1. Headache (pain in head)
  2. Renal impairment (severely reduced kidney function)
  3. Adverse drug reaction
  4. Bell's palsy (facial paralysis)
  5. Bruxism (habitual grinding of the teeth, typically during sleep)
  6. Endocarditis (inflammation in heart muscle)
  7. Migraine (headache)
  8. Pruritus (severe itching of the skin)
  9. Surgery
  10. Vitamin b1 increased

male:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Pain
  3. Cardiac failure congestive
  4. Decreased immune responsiveness
  5. Hepatic enzyme increased
  6. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  7. Hypoglycaemia (deficiency of glucose in the bloodstream)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Jardiance and Testosterone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pathological fracture (broken bone caused by disease)
  2. Renal failure (kidney dysfunction)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Ankle fracture
  5. Anxiety
  6. Bone density decreased
  7. Bone loss
  8. Chronic kidney disease
  9. Depression
  10. Emotional distress

40-49:

n/a

50-59:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Arthralgia (joint pain)
  3. Decreased immune responsiveness
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Hepatic enzyme increased
  6. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  7. Hypoglycaemia (deficiency of glucose in the bloodstream)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Productive cough

60+:

  1. Rash
  2. Back pain
  3. Weight increased
  4. Asthenia (weakness)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Burning sensation
  7. Cardiac failure congestive
  8. Catheter site pruritus (itching at the site)
  9. Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
  10. Cough

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 8 people, 14.55%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 10.91%
  3. Pituitary Tumor Benign: 4 people, 7.27%
  4. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 4 people, 7.27%
  5. Type 2 Diabetes: 3 people, 5.45%
  6. Malignant Melanoma Stage Iv (the cancer has spread to other places in the body, such as the lung, liver, brain, bone, soft tissue, or gastrointestinal (gi) tract. cancer may have spread to places in the skin far away from where it first started): 3 people, 5.45%
  7. Lung Cancer - Small Cell (lung cancer): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Jardiance and Testosterone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Jardiance and Testosterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Jardiance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Testosterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Jardiance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Testosterone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on empagliflozin and testosterone (the active ingredients of Jardiance and Testosterone, respectively), and Jardiance and Testosterone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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