Jardiance and Venclexta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Jardiance (empagliflozin) and Venclexta (venetoclax). Common drug interactions include acute myeloid leukaemia recurrent among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Jardiance and Venclexta. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Jardiance?

Jardiance has active ingredients of empagliflozin. It is often used in hyperglycemia. eHealthMe is studying from 44,457 Jardiance users. Check the latest studies of Jardiance.

What is Venclexta?

Venclexta has active ingredients of venetoclax. eHealthMe is studying from 31,425 Venclexta users. Check the latest studies of Venclexta.



On Jul, 19, 2026

91 people who take Jardiance and Venclexta together, and have interactions are studied.

Jardiance and Venclexta drug interactions.

What are the common drug interactions of Jardiance and Venclexta, by gender? *:

female:

  1. Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
  2. Confusional state
  3. Haemorrhage (bleeding)
  4. Nausea (feeling of having an urge to vomit)
  5. Platelet disorder
  6. Urinary tract infection
  7. Abdominal discomfort
  8. Acute respiratory failure
  9. Adverse drug reaction
  10. Asthenia (weakness)

male:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Diarrhoea
  3. Disease progression
  4. Viral infection
  5. Anal abscess
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Dizziness
  8. Death
  9. Muscular weakness (muscle weakness)
  10. Weight decreased

What are the common drug interactions of Jardiance and Venclexta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Staphylococcal infection (an infection with staphylococcus bacteria)

50-59:

  1. Flatulence (flatus expelled through the anus)
  2. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  3. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Disease progression
  6. Death
  7. Bacterial sepsis
  8. Escherichia infection (bacterial infection by escherichia coli)
  9. Fistula (an abnormal connection or passageway between two)
  10. Influenza

60+:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Diarrhoea
  3. Weight decreased
  4. Abdominal pain
  5. Angiopathy (generic term for a disease of the blood vessels)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Cardiac fibrillation (uncontrolled muscle contraction of heart)
  8. Carotid artery stenosis (narrowing of carotid artery)
  9. Gout (uric acid crystals building up in the body)
  10. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the existing conditions these people have? *

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 31 people, 34.07%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 30 people, 32.97%
  3. Diabetes: 13 people, 14.29%
  4. High Blood Pressure: 9 people, 9.89%
  5. Multiple Myeloma (cancer of the plasma cells): 8 people, 8.79%
  6. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 6 people, 6.59%
  7. Type 2 Diabetes: 5 people, 5.49%
  8. Pain: 5 people, 5.49%

* Approximation only. Some reports may have incomplete information.

Do you take Jardiance and Venclexta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Jardiance and Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Jardiance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Jardiance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Venclexta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on empagliflozin and venetoclax (the active ingredients of Jardiance and Venclexta, respectively), and Jardiance and Venclexta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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