Juxtapid and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Juxtapid (lomitapide mesylate) and Ambien (zolpidem tartrate). Common drug interactions include diarrhoea among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Juxtapid and Ambien. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Juxtapid?

Juxtapid has active ingredients of lomitapide mesylate. eHealthMe is studying from 4,279 Juxtapid users. Check the latest studies of Juxtapid.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.



On Jul, 10, 2026

50 people who take Juxtapid and Ambien together, and have interactions are studied.

Juxtapid and Ambien drug interactions.

What are the common drug interactions of Juxtapid and Ambien, by gender? *:

female:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Weight decreased
  4. Abdominal discomfort
  5. Hepatic enzyme increased
  6. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  7. Myalgia (muscle pain)
  8. Abdominal pain
  9. Abdominal pain upper
  10. Alanine aminotransferase increased

male:

  1. Diarrhoea
  2. Fatigue (feeling of tiredness)
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Asthenia (weakness)
  5. Blood calcium increased
  6. Blood insulin increased
  7. Blood parathyroid hormone increased
  8. Blood pressure decreased
  9. Dizziness
  10. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Juxtapid and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal discomfort
  2. Nausea (feeling of having an urge to vomit)

40-49:

  1. Hepatic enzyme increased
  2. Herpes zoster
  3. Weight decreased

50-59:

  1. Diarrhoea
  2. Hepatic enzyme increased
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Abdominal pain upper
  5. Nausea (feeling of having an urge to vomit)
  6. Flatulence (flatus expelled through the anus)
  7. Alanine aminotransferase increased
  8. Abdominal pain
  9. Dyspepsia (indigestion)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

  1. Diarrhoea
  2. Abdominal pain
  3. Gait disturbance
  4. Pain in extremity
  5. Back pain
  6. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  7. Peripheral swelling
  8. Anxiety
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. High Blood Pressure: 11 people, 22.00%
  2. Hyperlipidaemia (presence of excess lipids in the blood): 9 people, 18.00%
  3. High Blood Cholesterol: 5 people, 10.00%
  4. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 10.00%
  5. Bipolar Disorder (mood disorder): 5 people, 10.00%
  6. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 8.00%
  7. Allergic Rhinitis: 4 people, 8.00%
  8. Hypersensitivity: 3 people, 6.00%
  9. Gout (uric acid crystals building up in the body): 3 people, 6.00%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Juxtapid and Ambien?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Juxtapid and Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Juxtapid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Juxtapid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ambien and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lomitapide mesylate and zolpidem tartrate (the active ingredients of Juxtapid and Ambien, respectively), and Juxtapid and Ambien (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: