Juxtapid and Hydramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Juxtapid (lomitapide mesylate) and Hydramine (diphenhydramine hydrochloride). Common drug interactions include mental status changes among females and alcohol use among males.

The phase IV clinical study analyzes what interactions people have when they take Juxtapid and Hydramine. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Juxtapid?

Juxtapid has active ingredients of lomitapide mesylate. eHealthMe is studying from 4,279 Juxtapid users. Check the latest studies of Juxtapid.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

13 people who take Juxtapid and Hydramine together, and have interactions are studied.

Juxtapid and Hydramine drug interactions.

What are the common drug interactions of Juxtapid and Hydramine, by gender? *:

female:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Oropharyngeal pain
Arthralgia (joint pain)
Cough
Upper respiratory tract infection
Nausea (feeling of having an urge to vomit)
Weight decreased
Decreased appetite
Eructation (release of gas from the digestive tract)
Hepatic enzyme increased

male:

Alcohol use
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hepatic enzyme increased

What are the common drug interactions of Juxtapid and Hydramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Headache (pain in head)
Hepatic steatosis (fatty liver disease)
Hypertension (high blood pressure)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Arthralgia (joint pain)
Cough
Oropharyngeal pain
Upper respiratory tract infection
Weight decreased
Decreased appetite

60+:

Diarrhoea
Myalgia (muscle pain)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Oropharyngeal pain
Respiratory disorder (respiratory disease)

What are the existing conditions these people have? *

Rickets (softening of bones): 3 people, 23.08%
Nausea And Vomiting: 3 people, 23.08%
Nausea (feeling of having an urge to vomit): 3 people, 23.08%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 23.08%
Depression: 3 people, 23.08%
Chest Pain: 3 people, 23.08%
Carotid Artery Disease: 3 people, 23.08%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 7.69%
Cardiac Failure: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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