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Juxtapid and Maxzide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Juxtapid (lomitapide mesylate) and Maxzide (hydrochlorothiazide; triamterene). Common drug interactions include diarrhoea among females.

The phase IV clinical study analyzes what interactions people have when they take Juxtapid and Maxzide. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Juxtapid?

Juxtapid has active ingredients of lomitapide mesylate. eHealthMe is studying from 4,279 Juxtapid users. Check the latest studies of Juxtapid.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

On Aug, 10, 2026

12 people who take Juxtapid and Maxzide together, and have interactions are studied.

Juxtapid and Maxzide drug interactions.

What are the common drug interactions of Juxtapid and Maxzide, by gender? *:

female:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Low density lipoprotein increased (cholesterol increased in blood)
  4. Abdominal pain
  5. Back pain
  6. Vomiting
  7. Angina pectoris (chest pain due to ischemia of the heart muscle)
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Generalised oedema (swelling all over the body)
  10. Blood triglycerides increased

male:

n/a

What are the common drug interactions of Juxtapid and Maxzide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Generalised oedema (swelling all over the body)
  2. Diarrhoea
  3. Nausea (feeling of having an urge to vomit)
  4. Abdominal pain
  5. Back pain
  6. Vomiting
  7. Angina pectoris (chest pain due to ischemia of the heart muscle)
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

  1. Blood triglycerides increased
  2. Flatulence (flatus expelled through the anus)
  3. Low density lipoprotein increased (cholesterol increased in blood)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 9 people, 75.00%
  2. Indigestion: 7 people, 58.33%
  3. Hypersensitivity: 5 people, 41.67%
  4. Back Pain: 5 people, 41.67%
  5. Abdominal Pain: 5 people, 41.67%
  6. Abdominal Pain Upper: 3 people, 25.00%
  7. Stable Angina (a constant chest pain): 2 people, 16.67%
  8. Peripheral Arterial Occlusive Disease (reproducible ischemic muscle pain): 2 people, 16.67%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
  10. Gout (uric acid crystals building up in the body): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Juxtapid and Maxzide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Juxtapid and Maxzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Juxtapid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Maxzide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Juxtapid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxzide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lomitapide mesylate and hydrochlorothiazide; triamterene (the active ingredients of Juxtapid and Maxzide, respectively), and Juxtapid and Maxzide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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