Juxtapid and Pravachol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Juxtapid (lomitapide mesylate) and Pravachol (pravastatin sodium). Common drug interactions include weight decreased among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Juxtapid and Pravachol. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Juxtapid?

Juxtapid has active ingredients of lomitapide mesylate. eHealthMe is studying from 4,279 Juxtapid users. Check the latest studies of Juxtapid.

What is Pravachol?

Pravachol has active ingredients of pravastatin sodium. It is often used in high blood cholesterol. eHealthMe is studying from 24,382 Pravachol users. Check the latest studies of Pravachol.

On Jul, 17, 2026

18 people who take Juxtapid and Pravachol together, and have interactions are studied.

Juxtapid and Pravachol drug interactions.

What are the common drug interactions of Juxtapid and Pravachol, by gender? *:

female:

Weight decreased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Flushing (the warm, red condition of human skin)
Hyperhidrosis (abnormally increased sweating)
Low density lipoprotein increased (cholesterol increased in blood)
Blood pressure decreased
Constipation
Drug ineffective
Hepatic enzyme increased
Nausea (feeling of having an urge to vomit)

male:

Weight decreased
Diarrhoea
Myalgia (muscle pain)
Nightmare (unpleasant dream)
Poor quality sleep
Somnambulism (sleep walking)
Terminal insomnia (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired)
Therapeutic response unexpected
Constipation
Flatulence (flatus expelled through the anus)

What are the common drug interactions of Juxtapid and Pravachol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Constipation

40-49:

Constipation
Flatulence (flatus expelled through the anus)
Weight decreased
Weight increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Flushing (the warm, red condition of human skin)
Hyperhidrosis (abnormally increased sweating)
Low density lipoprotein increased (cholesterol increased in blood)

50-59:

Myalgia (muscle pain)
Nightmare (unpleasant dream)
Somnambulism (sleep walking)
Weight decreased
Hyperventilation

60+:

Weight decreased
Blood pressure decreased
Diarrhoea
Drug ineffective
Hepatic enzyme increased
Nausea (feeling of having an urge to vomit)
Poor quality sleep
Terminal insomnia (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired)
Therapeutic response unexpected

* Approximation only. Some reports may have incomplete information.

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