Kaletra and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kaletra (lopinavir; ritonavir) and Aredia (pamidronate disodium). Common drug interactions include abdominal discomfort among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Kaletra and Aredia. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Kaletra?

Kaletra has active ingredients of lopinavir; ritonavir. It is often used in hiv infection. eHealthMe is studying from 23,070 Kaletra users. Check the latest studies of Kaletra.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.



On Jul, 25, 2026

16 people who take Kaletra and Aredia together, and have interactions are studied.

Kaletra and Aredia drug interactions.

What are the common drug interactions of Kaletra and Aredia, by gender? *:

female:

  1. Abdominal discomfort
  2. Abdominal pain
  3. Alanine aminotransferase increased
  4. Anaemia (lack of blood)
  5. Anxiety
  6. Back pain
  7. Bacterial infection
  8. Blood triglycerides increased
  9. Bone infarction (ischemic death of the cellular elements of the bone and marrow)
  10. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

male:

  1. Abdominal pain
  2. Hypertension (high blood pressure)
  3. Cough
  4. Cyst (a closed sac)
  5. Diarrhoea
  6. Dysuria (painful or difficult urination)
  7. Ear discomfort
  8. Ear pain
  9. Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
  10. Facial pain

What are the common drug interactions of Kaletra and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
  2. Renal failure chronic (long lasting kidney dysfunction)

60+:

n/a

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 1 person, 6.25%
  2. Drug Exposure During Pregnancy: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Kaletra and Aredia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Kaletra and Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Kaletra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kaletra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aredia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lopinavir; ritonavir and pamidronate disodium (the active ingredients of Kaletra and Aredia, respectively), and Kaletra and Aredia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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