Kalydeco and Ergocalciferol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Kalydeco (ivacaftor) and Ergocalciferol (ergocalciferol). Common drug interactions include forced expiratory volume decreased among females and infective pulmonary exacerbation of cystic fibrosis among males.
The phase IV clinical study analyzes what interactions people have when they take Kalydeco and Ergocalciferol. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Kalydeco?
Kalydeco has active ingredients of ivacaftor. eHealthMe is studying from 6,652 Kalydeco users. Check the latest studies of Kalydeco.
What is Ergocalciferol?
Ergocalciferol has active ingredients of ergocalciferol. It is often used in rickets. eHealthMe is studying from 32,652 Ergocalciferol users. Check the latest studies of Ergocalciferol.
11 people who take Kalydeco and Ergocalciferol together, and have interactions are studied.

What are the common drug interactions of Kalydeco and Ergocalciferol, by gender? *:
female:
- Forced expiratory volume decreased (decreased lung expired air volume)
- Hypophagia (reduced food intake)
- Intentional self-injury
- Suicidal ideation
- Pulmonary congestion (congestion in the lungs)
- Abdominal pain upper
- Asthenia (weakness)
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
- Chest pain
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
male:
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Distal ileal obstruction syndrome (blockage of the intestines by thickened stool and occurs in individuals with cystic fibrosis)
- Fall
- Hyperglycaemia (high blood sugar)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Joint swelling
- Pancreatitis (inflammation of pancreas)
What are the common drug interactions of Kalydeco and Ergocalciferol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Osteomyelitis (infection of bone)
10-19:
- Cystic fibrosis (disease of the secretary glands)
- Depression
- Forced expiratory volume decreased (decreased lung expired air volume)
- Hypophagia (reduced food intake)
- Intentional self-injury
- Suicidal ideation
- Weight decreased
- Transaminases increased
20-29:
- Fall
- Hyperglycaemia (high blood sugar)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Joint swelling
30-39:
- Distal ileal obstruction syndrome (blockage of the intestines by thickened stool and occurs in individuals with cystic fibrosis)
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
40-49:
- Abdominal pain upper
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Nausea (feeling of having an urge to vomit)
- Nephrolithiasis (calculi in the kidneys)
- Presyncope
- Pulmonary embolism (blockage of the main artery of the lung)
- Pyrexia (fever)
- Weight decreased
- Asthenia (weakness)
50-59:
- Pancreatitis (inflammation of pancreas)
60+:
n/a
What are the existing conditions these people have? *
- Cystic Fibrosis (disease of the secretary glands): 11 people, 100.00%
- Respiratory Tract Inflammation: 1 person, 9.09%
- Respiratory Disorder (respiratory disease): 1 person, 9.09%
- Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 9.09%
- Nausea (feeling of having an urge to vomit): 1 person, 9.09%
- Cystic Fibrosis Lung (fibrosis with cyst in the lung): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Kalydeco and Ergocalciferol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Kalydeco (6,652 reports)
- Ergocalciferol (32,652 reports)
Browse all drug interactions of Kalydeco and Ergocalciferol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Kalydeco:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ergocalciferol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Kalydeco and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ergocalciferol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on ivacaftor and ergocalciferol (the active ingredients of Kalydeco and Ergocalciferol, respectively), and Kalydeco and Ergocalciferol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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