Kenalog and Opsumit drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kenalog (triamcinolone acetonide) and Opsumit (macitentan). Common drug interactions include dyspnoea among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Kenalog and Opsumit. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Kenalog?

Kenalog has active ingredients of triamcinolone acetonide. It is often used in pain. eHealthMe is studying from 10,692 Kenalog users. Check the latest studies of Kenalog.

What is Opsumit?

Opsumit has active ingredients of macitentan. eHealthMe is studying from 67,926 Opsumit users. Check the latest studies of Opsumit.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

11 people who take Kenalog and Opsumit together, and have interactions are studied.

What are the common drug interactions of Kenalog and Opsumit, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Abscess (pus)
Alopecia (absence of hair from areas of the body)
Chest pain
Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
Headache (pain in head)
Loss of consciousness

male:

Acute respiratory failure
Altered state of consciousness (altered state of mind)
Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
Stupor (lack of critical cognitive function and level of consciousness)
Oedema (fluid collection in tissue)
Urine output decreased
Asthma
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Kenalog and Opsumit, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abscess (pus)
Alopecia (absence of hair from areas of the body)
Chest pain
Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Headache (pain in head)
Loss of consciousness
Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

n/a

50-59:

Acute respiratory failure
Anticoagulation drug level below therapeutic
Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
Cerebral haemorrhage (bleeding within the brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hypertension (high blood pressure)
Pulmonary arterial pressure increased
Pupil fixed
Pupillary reflex impaired

60+:

Dyspnoea (difficult or laboured respiration)
Acute respiratory failure
Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
Stupor (lack of critical cognitive function and level of consciousness)
Acute right ventricular failure (acute heart attack)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood pressure decreased
Cough

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 81.82%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 36.36%
Nausea (feeling of having an urge to vomit): 2 people, 18.18%
Muscle Spasms (muscle contraction): 2 people, 18.18%
Tardive Dyskinesia (a disorder that involves involuntary movements): 1 person, 9.09%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 1 person, 9.09%
Migraine (headache): 1 person, 9.09%
Itching: 1 person, 9.09%
Impaired Gastric Emptying: 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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