Keppra and Adapalene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keppra (levetiracetam) and Adapalene (adapalene). Common drug interactions include dry skin among females and dry skin among males.

The phase IV clinical study analyzes what interactions people have when they take Keppra and Adapalene. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

What is Adapalene?

Adapalene has active ingredients of adapalene. It is often used in acne. eHealthMe is studying from 174,662 Adapalene users. Check the latest studies of Adapalene.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

20 people who take Keppra and Adapalene together, and have interactions are studied.

What are the common drug interactions of Keppra and Adapalene, by gender? *:

female:

Dry skin
Rash papular (redness with papule)
Chemical burn of skin
Adverse drug reaction
Drug ineffective
Hypersensitivity
Overdose
Pain of skin
Rash
Skin discolouration (change of skin colour)

male:

Dry skin
Skin irritation
Drug ineffective
Erythema (redness of the skin)
Pruritus (severe itching of the skin)

What are the common drug interactions of Keppra and Adapalene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Skin burning sensation
Skin irritation
Erythema (redness of the skin)
Rash macular (small, flat red spots)
Drug ineffective
Dry skin
Skin exfoliation (removal of the oldest dead skin cells)
Hypersensitivity
Overdose
Rash

20-29:

Dry skin
Pruritus (severe itching of the skin)
Skin burning sensation
Skin discolouration (change of skin colour)
Skin exfoliation (removal of the oldest dead skin cells)
Skin mass
Adverse drug reaction

30-39:

Skin burning sensation
Dry skin
Chemical burn of skin
Erythema (redness of the skin)
Rash macular (small, flat red spots)
Skin irritation
Pain of skin
Rash papular (redness with papule)
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 10.00%
Skin Discoloration: 1 person, 5.00%
Rash Papular (redness with papule): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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