Keppra and Ascorbate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Keppra (levetiracetam) and Ascorbate (vitamin c (ascorbic acid)). Common drug interactions include abdominal discomfort among females and basal cell carcinoma among males.
The phase IV clinical study analyzes what interactions people have when they take Keppra and Ascorbate. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Keppra?
Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.
What is Ascorbate?
Ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 1,446 Ascorbate users. Check the latest studies of Ascorbate.
11 people who take Keppra and Ascorbate together, and have interactions are studied.

What are the common drug interactions of Keppra and Ascorbate, by gender? *:
female:
- Abdominal discomfort
- Diarrhoea
- Disturbance in attention
- Dizziness
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
- Headache (pain in head)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
- Insomnia (sleeplessness)
male:
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Confusional state
- Skin striae (irregular areas of skin that look like bands, stripes, or lines)
- Weight increased
- Fall
- Pathological fracture (broken bone caused by disease)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Back pain
- Bone loss
- Fatigue (feeling of tiredness)
What are the common drug interactions of Keppra and Ascorbate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Weight increased
- Abdominal discomfort
- Diarrhoea
- Dizziness
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
- Headache (pain in head)
- Insomnia (sleeplessness)
- Back pain
- Bone loss
50-59:
- Neutropenia (an abnormally low number of neutrophils)
60+:
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Confusional state
- Disturbance in attention
- Fall
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
- Pathological fracture (broken bone caused by disease)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Fatigue (feeling of tiredness)
What are the existing conditions these people have? *
- Wheezing (a high-pitched whistling sound made while you breath): 2 people, 18.18%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 18.18%
- Peripheral Ischaemia (impaired circulation to an extremity): 2 people, 18.18%
- Pain: 2 people, 18.18%
- Otitis (ear infection): 2 people, 18.18%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 18.18%
- Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 18.18%
- Urinary Tract Infection: 1 person, 9.09%
- Upper Respiratory Tract Infection: 1 person, 9.09%
- Iga Nephropathy (kidney disease- condition prevents the kidneys from filtering waste): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Keppra and Ascorbate?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Keppra and Ascorbate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Keppra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ascorbate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keppra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ascorbate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on levetiracetam and vitamin c (ascorbic acid) (the active ingredients of Keppra and Ascorbate, respectively), and Keppra and Ascorbate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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