Keppra and Mucomyst drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Keppra (levetiracetam) and Mucomyst (acetylcysteine). Common drug interactions include pneumonia among females and hypertension among males.
The phase IV clinical study analyzes what interactions people have when they take Keppra and Mucomyst. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Keppra?
Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.
What is Mucomyst?
Mucomyst has active ingredients of acetylcysteine. eHealthMe is studying from 1,835 Mucomyst users. Check the latest studies of Mucomyst.
39 people who take Keppra and Mucomyst together, and have interactions are studied.

What are the common drug interactions of Keppra and Mucomyst, by gender? *:
female:
- Pneumonia
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Muscular weakness (muscle weakness)
- Blood glucose increased
- Cardiac arrest
- Dehydration (dryness resulting from the removal of water)
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Lethargy (tiredness)
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
- Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
male:
- Hypertension (high blood pressure)
- Infection
- Fall
- Hyperkalaemia (damage to or disease of the kidney)
- Hypotension (abnormally low blood pressure)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Pneumonia
- Renal failure (kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Sepsis (a severe blood infection that can lead to organ failure and death)
What are the common drug interactions of Keppra and Mucomyst, by age (0-1 to 60+)? *:
0-1:
- Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
2-9:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Muscular weakness (muscle weakness)
- Pneumonia
- Hypertension (high blood pressure)
- Infection
- Anticonvulsant drug level below therapeutic
- Blood glucose increased
- Cardiac arrest
- Dehydration (dryness resulting from the removal of water)
- Hypovolaemia (a decreased volume of circulating blood in the body)
10-19:
- Pneumonia
- Respiratory tract infection
20-29:
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
30-39:
n/a
40-49:
- Hiv antibody positive
- Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
- Aphasia (damage to the parts of the brain that control language)
- Confusional state
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Tremor (trembling or shaking movements in one or more parts of your body)
50-59:
- Hypertensive hydrocephalus (abnormal expansion of cavities (ventricles) within the brain that is caused by high blood pressure)
- Pruritus (severe itching of the skin)
60+:
- Crystal nephropathy (crystal induced injury to kidney)
- Atelectasis (partial or complete collapse of the lung)
- Renal failure (kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Sputum increased
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Dyspnoea (difficult or laboured respiration)
- Electrolyte imbalance
- Fall
What are the existing conditions these people have? *
- Pain: 8 people, 20.51%
- Fever: 8 people, 20.51%
- Hypotension (abnormally low blood pressure): 6 people, 15.38%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 6 people, 15.38%
- Cerebral Palsy: 5 people, 12.82%
- Renal Tubular Acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys): 5 people, 12.82%
- Agitation (state of anxiety or nervous excitement): 5 people, 12.82%
- Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 12.82%
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 5 people, 12.82%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 12.82%
* Approximation only. Some reports may have incomplete information.
Do you take Keppra and Mucomyst?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Keppra and Mucomyst:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Keppra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mucomyst:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keppra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mucomyst and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on levetiracetam and acetylcysteine (the active ingredients of Keppra and Mucomyst, respectively), and Keppra and Mucomyst (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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