Keppra and Tukysa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keppra (levetiracetam) and Tukysa (tucatinib). Common drug interactions include diarrhoea among females.

The phase IV clinical study analyzes what interactions people have when they take Keppra and Tukysa. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

What is Tukysa?

Tukysa has active ingredients of tucatinib. eHealthMe is studying from 3,216 Tukysa users. Check the latest studies of Tukysa.

On Jul, 19, 2026

67 people who take Keppra and Tukysa together, and have interactions are studied.

What are the common drug interactions of Keppra and Tukysa, by gender? *:

female:

Diarrhoea
Confusional state
Blood potassium decreased
Photosensitivity reaction
Skin hypertrophy (skin cells enlarges)
Memory impairment
Administration site pain
Coma (state of unconsciousness lasting more than six hours)
Constipation
Hypercapnia (too much smoke)

male:

n/a

What are the common drug interactions of Keppra and Tukysa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypoaesthesia (reduced sense of touch or sensation)
Somnolence (a state of near-sleep, a strong desire for sleep)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Constipation
Dizziness
Fatigue (feeling of tiredness)
Headache (pain in head)
Metastasis (spreadable cancer to other organ from origin)
Erythema (redness of the skin)
Gait disturbance

40-49:

Diarrhoea
Hypokalaemia (low potassium)
Soft tissue infection
Syncope (loss of consciousness with an inability to maintain postural tone)
Fatigue (feeling of tiredness)
Asthenia (weakness)
Decreased appetite
Fall
Haematocrit decreased
Haemoglobin decreased

50-59:

Adverse drug reaction
Diarrhoea
Dizziness
Hepatic enzyme increased
Joint swelling
Neuropathy peripheral (surface nerve damage)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Peripheral swelling
Stomatitis (inflammation of mucous membrane of mouth)
Fatigue (feeling of tiredness)

60+:

Confusional state
Coma (state of unconsciousness lasting more than six hours)
Hypercapnia (too much smoke)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Catatonia (unresponsive to external stimuli)
Decreased appetite
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)
Fall
Vomiting

What are the existing conditions these people have? *

Breast Cancer Female: 23 people, 34.33%
Osteoporotic Fracture (fracture due to weak bone): 17 people, 25.37%
Breast Cancer: 15 people, 22.39%
Diarrhea: 8 people, 11.94%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 7.46%
Embolism Venous (embolus may pass into the arterial system): 5 people, 7.46%

* Approximation only. Some reports may have incomplete information.

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