Keppra and Zerbaxa drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Keppra (levetiracetam) and Zerbaxa (ceftolozane sulfate; tazobactam sodium). Common drug interactions include pancytopenia among males.
The phase IV clinical study analyzes what interactions people have when they take Keppra and Zerbaxa. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.
What is Keppra?
Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.
What is Zerbaxa?
Zerbaxa has active ingredients of ceftolozane sulfate; tazobactam sodium. eHealthMe is studying from 1,018 Zerbaxa users. Check the latest studies of Zerbaxa.
51 people who take Keppra and Zerbaxa together, and have interactions are studied.
What are the common drug interactions of Keppra and Zerbaxa, by gender? *:
female:
n/a
male:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Confusional state
- White blood cell count decreased
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cellulitis (infection under the skin)
- Adverse event
- Bacterial infection
- Drug ineffective
- Marrow hyperplasia (increased bone marrow)
- Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
What are the common drug interactions of Keppra and Zerbaxa, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- White blood cell count decreased
- Confusional state
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cellulitis (infection under the skin)
- Bacterial infection
- Drug ineffective
- Marrow hyperplasia (increased bone marrow)
- Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
- Roseolovirus test positive
50-59:
- Adverse event
60+:
n/a
What are the existing conditions these people have? *
- Pain: 49 people, 96.08%
- High Blood Pressure: 49 people, 96.08%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 49 people, 96.08%
- Fungal Infection: 49 people, 96.08%
- Diarrhea: 49 people, 96.08%
- Cellulitis (infection under the skin): 49 people, 96.08%
- Abdominal Pain: 37 people, 72.55%
- Fever: 34 people, 66.67%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Keppra and Zerbaxa?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Keppra and Zerbaxa:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Keppra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zerbaxa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keppra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zerbaxa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on levetiracetam and ceftolozane sulfate; tazobactam sodium (the active ingredients of Keppra and Zerbaxa, respectively), and Keppra and Zerbaxa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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