Ketoconazole and Adalat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Adalat (nifedipine). Common drug interactions include abdominal pain among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Adalat. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

16 people who take Ketoconazole and Adalat together, and have interactions are studied.

Ketoconazole and Adalat drug interactions.

What are the common drug interactions of Ketoconazole and Adalat, by gender? *:

female:

Abdominal pain
Abdominal wall haematoma (abdominal wall blood clotting)
Haemoglobin decreased
Cataract (clouding of the lens inside the eye)
Chronic kidney disease
Renal failure (kidney dysfunction)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Blood glucose decreased
Graft rejection (graft failure)

male:

Alanine aminotransferase increased
Blood bilirubin increased
Drug abuser
Haemoglobin decreased
Headache (pain in head)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatocellular injury (liver injury)
Hepatotoxicity (chemical-driven liver damage)
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the common drug interactions of Ketoconazole and Adalat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood glucose decreased
Graft rejection (graft failure)
Sweating increased (excess sweating)

40-49:

n/a

50-59:

Anxiety
Chronic kidney disease
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug abuser
Renal failure (kidney dysfunction)

60+:

Haemoglobin decreased
Abdominal pain
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Colon dysplasia (abnormal growth or development of cells of colon)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Dizziness
Headache (pain in head)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatocellular injury (liver injury)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
Pain: 3 people, 18.75%
Cardiac Failure Chronic: 3 people, 18.75%
Dyslipidaemia (abnormal amount of lipids): 3 people, 18.75%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 12.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 12.50%
Cardiac Failure: 2 people, 12.50%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 12.50%
Diabetes: 2 people, 12.50%
Blood Calcium Decreased: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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