Ketoconazole and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Aredia (pamidronate disodium). Common drug interactions include back pain among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Aredia. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.

On Jul, 10, 2026

97 people who take Ketoconazole and Aredia together, and have interactions are studied.

Ketoconazole and Aredia drug interactions.

What are the common drug interactions of Ketoconazole and Aredia, by gender? *:

female:

Back pain
Dysphagia (a condition in which swallowing is difficult or painful)
Insomnia (sleeplessness)
Anxiety
Osteonecrosis of jaw (death of bone of jaw)
Anaemia (lack of blood)
Confusional state
Spinal osteoarthritis (joint cartilage loss in spine)
Herpes zoster
Osteomyelitis (infection of bone)

male:

Pain
Osteonecrosis of jaw (death of bone of jaw)
Anaemia (lack of blood)
Renal cyst (kidney cyst)
Weight decreased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Disability
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Nephrolithiasis (calculi in the kidneys)
Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Ketoconazole and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abscess (pus)
Acquired oesophageal web (structural abnormalities in the oesophagus)
Actinic keratosis (skin disease due to sun exposure)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atelectasis (partial or complete collapse of the lung)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)

20-29:

n/a

30-39:

Abdominal pain
Anaemia (lack of blood)
Anxiety
Appendicitis (inflammation of the appendix)
Arthropathy
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Bone pain
Breast cancer recurrent
Confusional state
Constipation

40-49:

Pain
Dysarthria (speech disorder)
Hypertension (high blood pressure)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Depression
Dyspnoea (difficult or laboured respiration)
Hyperlipidaemia (presence of excess lipids in the blood)
Neuropathy peripheral (surface nerve damage)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Weight decreased

50-59:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pain
Pain in extremity
Abdominal pain
Altered state of consciousness (altered state of mind)
Anaemia (lack of blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety
Back pain

60+:

Back pain
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Thrombocytopenia (decrease of platelets in blood)
Weight decreased
Injury
Pain in jaw
Hyperlipidaemia (presence of excess lipids in the blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 24 people, 24.74%
Prostate Cancer: 23 people, 23.71%
High Blood Cholesterol: 22 people, 22.68%
Osteoporosis (bones weak and more likely to break): 14 people, 14.43%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 13 people, 13.40%
Haemorrhage (bleeding): 11 people, 11.34%
Breast Cancer Metastatic: 11 people, 11.34%
Aortic Valve Incompetence: 11 people, 11.34%
Depression: 8 people, 8.25%
Metastases To Prostate (cancer spreads to prostate): 7 people, 7.22%

* Approximation only. Some reports may have incomplete information.

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