Ketoconazole and Cholestyramine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Cholestyramine (cholestyramine). Common drug interactions include anxiety among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Cholestyramine. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.
What is Ketoconazole?
Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.
What is Cholestyramine?
Cholestyramine has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 9,893 Cholestyramine users. Check the latest studies of Cholestyramine.
70 people who take Ketoconazole and Cholestyramine together, and have interactions are studied.

What are the common drug interactions of Ketoconazole and Cholestyramine, by gender? *:
female:
- Anxiety
- Cellulitis (infection under the skin)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Drug ineffective
- Fall
- Folliculitis (infection of hair root)
- Groin abscess (pus in groin)
- Injury
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Pain in extremity
male:
- Pain
- Anxiety
- Constipation
- Depression
- Osteopenia (a condition where bone mineral density is lower than normal)
- Renal failure (kidney dysfunction)
- Weight decreased
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Blood alkaline phosphatase increased
- Blood creatine phosphokinase increased
What are the common drug interactions of Ketoconazole and Cholestyramine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anxiety
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Emotional distress
- General physical health deterioration (weak health status)
- Injury
- Myocardial strain
- Pain
- Pulmonary embolism (blockage of the main artery of the lung)
30-39:
- Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
- Behcet's syndrome (involves inflammation of the blood vessels)
- Depression
- Incoherent (talking in a confused and unclear way)
- Weight increased
40-49:
- Depression
- Blood creatine phosphokinase increased
- Difficulty in walking
- Myalgia (muscle pain)
- Myopathy toxic (a muscular disease in which the muscle fibres do not function due to toxin)
- Asthenia (weakness)
- Dyspnoea (difficult or laboured respiration)
- Hypertension (high blood pressure)
- Weight decreased
- Blood pressure increased
50-59:
- Drug ineffective
- Emotional distress
- Fracture
- Hip fracture
- Hyperlipidaemia (presence of excess lipids in the blood)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Multiple fractures
- Nephrogenic anaemia (anaemia due to kidney disease)
- Non-alcoholic steatohepatitis (liver inflammation caused by a build up of fat in the liver)
- Osteoporosis (bones weak and more likely to break)
60+:
- Urinary retention (the inability to completely or partially empty the bladder)
- Constipation
- Leukopenia (less number of white blood cells in blood)
- Neutropenia (an abnormally low number of neutrophils)
- Pain
- Pneumonia
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Nausea (feeling of having an urge to vomit)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
What are the existing conditions these people have? *
- High Blood Pressure: 15 people, 21.43%
- High Blood Cholesterol: 13 people, 18.57%
- Stress And Anxiety: 12 people, 17.14%
- Inflammation: 12 people, 17.14%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 15.71%
- Pain: 11 people, 15.71%
- Hypersensitivity: 9 people, 12.86%
- Hiv Infection: 9 people, 12.86%
- Migraine (headache): 9 people, 12.86%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 8 people, 11.43%
* Approximation only. Some reports may have incomplete information.
Do you take Ketoconazole and Cholestyramine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Ketoconazole (16,014 reports)
- Cholestyramine (9,893 reports)
Browse all drug interactions of Ketoconazole and Cholestyramine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ketoconazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cholestyramine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ketoconazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cholestyramine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ketoconazole and cholestyramine (the active ingredients of Ketoconazole and Cholestyramine, respectively), and Ketoconazole and Cholestyramine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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