Ketoconazole and Indapamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Indapamide (indapamide). Common drug interactions include arthralgia among females and renal impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Indapamide. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Indapamide?

Indapamide has active ingredients of indapamide. It is often used in high blood pressure. eHealthMe is studying from 22,152 Indapamide users. Check the latest studies of Indapamide.



On Jul, 30, 2026

48 people who take Ketoconazole and Indapamide together, and have interactions are studied.

Ketoconazole and Indapamide drug interactions.

What are the common drug interactions of Ketoconazole and Indapamide, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Back disorder
  3. Back pain
  4. Gait disturbance
  5. Joint stiffness
  6. Muscular weakness (muscle weakness)
  7. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  8. Pain in extremity
  9. Impaired self-care
  10. Drug ineffective

male:

  1. Renal impairment (severely reduced kidney function)
  2. Blood alkaline phosphatase increased
  3. Volvulus (obstruction caused by twisting of the stomach or intestine)
  4. Angioedema (rapid swelling of the dermis)
  5. Bone marrow failure
  6. Cardiac failure congestive
  7. Cardiotoxicity (damage to the heart muscle)
  8. Chest pain
  9. Electrolyte imbalance
  10. Embolism arterial (blood clot that has travelled through your arteries and become stuck)

What are the common drug interactions of Ketoconazole and Indapamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Angioedema (rapid swelling of the dermis)
  2. Constipation
  3. Decreased appetite
  4. Dizziness
  5. Loss of consciousness
  6. Rash erythematous (redness of the skin)
  7. Weight decreased

30-39:

  1. Bone marrow failure
  2. Cardiotoxicity (damage to the heart muscle)
  3. Electrolyte imbalance
  4. Embolism arterial (blood clot that has travelled through your arteries and become stuck)
  5. Hepatotoxicity (chemical-driven liver damage)
  6. Inflammation

40-49:

  1. Depressed mood
  2. Emotional poverty
  3. Impaired work ability
  4. Renal failure (kidney dysfunction)
  5. Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

  1. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  2. Asthenia (weakness)
  3. Blindness
  4. Bone disorder
  5. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  6. Diarrhoea
  7. Disseminated tuberculosis
  8. Dysgeusia (disorder of the sense of taste)
  9. Scotoma (an area of diminished vision within the visual field)
  10. Vision blurred

60+:

  1. Lip swelling
  2. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
  3. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
  4. Agitation (state of anxiety or nervous excitement)
  5. Angioedema (rapid swelling of the dermis)
  6. Asthenia (weakness)
  7. Benign prostatic hyperplasia (benign enlargement of the prostate)
  8. Bladder cancer
  9. Death
  10. Disseminated tuberculosis

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 16.67%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 12.50%
  3. Psoriasis (immune-mediated disease that affects the skin): 5 people, 10.42%
  4. Gout (uric acid crystals building up in the body): 4 people, 8.33%
  5. Diabetes: 4 people, 8.33%
  6. Renal Cell Carcinoma (a kidney cancer): 3 people, 6.25%
  7. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 6.25%
  8. Infection Parasitic: 3 people, 6.25%
  9. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 6.25%
  10. Hypersensitivity: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Ketoconazole and Indapamide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ketoconazole and Indapamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ketoconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Indapamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ketoconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Indapamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ketoconazole and indapamide (the active ingredients of Ketoconazole and Indapamide, respectively), and Ketoconazole and Indapamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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