Ketoconazole and Mitoxantrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Mitoxantrone (mitoxantrone hydrochloride). Common drug interactions include back pain among females and hypokalaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Mitoxantrone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

17 people who take Ketoconazole and Mitoxantrone together, and have interactions are studied.

Ketoconazole and Mitoxantrone drug interactions.

What are the common drug interactions of Ketoconazole and Mitoxantrone, by gender? *:

female:

Back pain

male:

Hypokalaemia (low potassium)
Leukopenia (less number of white blood cells in blood)
Gingival infection (gum infection)
Haemoglobin decreased
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Lymph node pain
Lymphadenopathy (disease or enlargement of lymph nodes)
Mucosal inflammation (infection of mucous membrane)
Pain in jaw

What are the common drug interactions of Ketoconazole and Mitoxantrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Back pain

30-39:

n/a

40-49:

n/a

50-59:

Anaemia (lack of blood)
Back pain
Disease progression
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Heart rate irregular
Malaise (a feeling of general discomfort or uneasiness)
Metastasis (spreadable cancer to other organ from origin)
Muscle spasms (muscle contraction)
Night sweats (sweating in night)

60+:

Osteonecrosis (death of bone)
Bone disorder
Tooth abscess (pus formation in tooth)
Tooth deposit
Tooth extraction
Toothache (tooth pain)
Aseptic necrosis bone
Hypokalaemia (low potassium)
Jaw disorder (jaw disease)
Leukopenia (less number of white blood cells in blood)

What are the existing conditions these people have? *

Prostate Cancer Metastatic: 10 people, 58.82%
Prostate Cancer: 6 people, 35.29%
Metastases To Bone (cancer spreads to bone): 3 people, 17.65%
Pain: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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