Ketoconazole and Valchlor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Valchlor (mechlorethamine hydrochloride). Common drug interactions include pruritus among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Valchlor. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Valchlor?

Valchlor has active ingredients of mechlorethamine hydrochloride. eHealthMe is studying from 2,539 Valchlor users. Check the latest studies of Valchlor.

On Jul, 21, 2026

26 people who take Ketoconazole and Valchlor together, and have interactions are studied.

Ketoconazole and Valchlor drug interactions.

What are the common drug interactions of Ketoconazole and Valchlor, by gender? *:

female:

Pruritus (severe itching of the skin)
Erythema (redness of the skin)
Drug ineffective
Dermatitis allergic (inflammation of the skin due allergic reaction)
Pharyngeal hypoaesthesia (pharyngeal -abnormally decreased sensitivity)
Rash pruritic (redness with itching)
Urticaria (rash of round, red welts on the skin that itch intensely)
Abnormal dreams
Application site burn
Application site erythema (redness of the skin at application site)

male:

Pruritus (severe itching of the skin)
Application site irritation
Death
Device related infection
Fatigue (feeling of tiredness)
Jugular vein thrombosis (clot in jugular vein)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Pain
Pyrexia (fever)

What are the common drug interactions of Ketoconazole and Valchlor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nasopharyngitis (inflammation of the nasopharynx)

50-59:

Erythema (redness of the skin)
Pigmentation disorder (disturbances of human skin colour)
Pruritus (severe itching of the skin)
Skin burning sensation
Application site erosion
Application site inflammation
Application site pain
Gastrointestinal pain
Glaucoma (increased fluid pressure in the eye with vision loss)
Lymphadenopathy (disease or enlargement of lymph nodes)

60+:

Pruritus (severe itching of the skin)
Application site pruritus (application site severe itching of the skin)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Pain
Pyrexia (fever)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Pharyngeal hypoaesthesia (pharyngeal -abnormally decreased sensitivity)
Rash pruritic (redness with itching)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the existing conditions these people have? *

Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 12 people, 46.15%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 9 people, 34.62%

* Approximation only. Some reports may have incomplete information.

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