Ketoprofen and Buscopan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoprofen (ketoprofen) and Buscopan (hyoscine butylbromide). Common drug interactions include bone neoplasm among females and hepatic encephalopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoprofen and Buscopan. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoprofen?

Ketoprofen has active ingredients of ketoprofen. It is often used in pain. eHealthMe is studying from 15,048 Ketoprofen users. Check the latest studies of Ketoprofen.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.



On Jul, 16, 2026

36 people who take Ketoprofen and Buscopan together, and have interactions are studied.

Ketoprofen and Buscopan drug interactions.

What are the common drug interactions of Ketoprofen and Buscopan, by gender? *:

female:

  1. Bone neoplasm (tumour of bone)
  2. Vaginal discharge
  3. Vulvovaginal discomfort
  4. Vulvovaginal mycotic infection (vulvovaginal fungal infection)
  5. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  6. Neutropenia (an abnormally low number of neutrophils)
  7. Oedema peripheral (superficial swelling)
  8. Compression fracture (fracture due to pressure caused by injury)
  9. Haemochromatosis (body to absorb more iron than usual from food)
  10. Neck pain

male:

  1. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  2. Pancreatitis acute (sudden inflammation of pancreas)
  3. Haemoglobin decreased
  4. Hypokalaemia (low potassium)
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  6. Oedema (fluid collection in tissue)
  7. Pneumonia
  8. Pyrexia (fever)
  9. Renal impairment (severely reduced kidney function)
  10. Urinary tract infection

What are the common drug interactions of Ketoprofen and Buscopan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Vaginal discharge
  2. Vulvovaginal discomfort
  3. Vulvovaginal mycotic infection (vulvovaginal fungal infection)
  4. Appendicitis (inflammation of the appendix)
  5. Back pain
  6. Cystitis (inflammation of the wall of the bladder)
  7. Dehydration (dryness resulting from the removal of water)
  8. Diarrhoea
  9. Dyslipidaemia (abnormal amount of lipids)
  10. Gastroenteritis (inflammation of stomach and intestine)

30-39:

  1. Colitis (inflammation of colon)
  2. Haemoglobin decreased

40-49:

  1. Bone neoplasm (tumour of bone)

50-59:

  1. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Oedema peripheral (superficial swelling)
  4. Blood pressure decreased
  5. Depressed level of consciousness
  6. Pneumonia
  7. Pyrexia (fever)
  8. Transaminases increased
  9. Vomiting

60+:

  1. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  2. Pancreatitis acute (sudden inflammation of pancreas)
  3. Blood alkaline phosphatase increased
  4. Chest pain
  5. Constipation
  6. Delirium (wild excitement)
  7. Diffuse large b-cell lymphoma stage iii (cancer of b cells, a type of white blood cell-stage iii)
  8. Fungal infection
  9. Hypokalaemia (low potassium)
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

What are the existing conditions these people have? *

  1. Constipation: 12 people, 33.33%
  2. Abdominal Pain: 10 people, 27.78%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 27.78%
  4. Lung Cancer - Non-Small Cell (lung cancer): 6 people, 16.67%
  5. Agitation (state of anxiety or nervous excitement): 5 people, 13.89%
  6. Depression: 5 people, 13.89%
  7. Fever: 5 people, 13.89%
  8. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 13.89%
  9. Nausea And Vomiting: 4 people, 11.11%
  10. Insomnia (sleeplessness): 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Ketoprofen and Buscopan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ketoprofen and Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ketoprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ketoprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buscopan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ketoprofen and hyoscine butylbromide (the active ingredients of Ketoprofen and Buscopan, respectively), and Ketoprofen and Buscopan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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