Ketoprofen and Cephalexin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoprofen (ketoprofen) and Cephalexin (cephalexin). Common drug interactions include hypoaesthesia among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoprofen and Cephalexin. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoprofen?

Ketoprofen has active ingredients of ketoprofen. It is often used in pain. eHealthMe is studying from 15,048 Ketoprofen users. Check the latest studies of Ketoprofen.

What is Cephalexin?

Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,580 Cephalexin users. Check the latest studies of Cephalexin.



On Aug, 09, 2026

77 people who take Ketoprofen and Cephalexin together, and have interactions are studied.

Ketoprofen and Cephalexin drug interactions.

What are the common drug interactions of Ketoprofen and Cephalexin, by gender? *:

female:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Back pain
  3. Depression
  4. Hypertension (high blood pressure)
  5. Intervertebral disc degeneration (spinal disc degeneration)
  6. Anaemia (lack of blood)
  7. Ankle fracture
  8. Atelectasis (partial or complete collapse of the lung)
  9. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  10. Blood creatinine increased

male:

  1. Depression
  2. Renal failure (kidney dysfunction)
  3. Chronic kidney disease
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Headache (pain in head)
  6. Hepatocellular damage (liver damage)
  7. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  10. Blood glucose increased

What are the common drug interactions of Ketoprofen and Cephalexin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Ligament disorder (disease of ligament)

10-19:

  1. Middle ear effusion (fluid in middle ear)
  2. Otitis media (inflammation of the middle ear)
  3. Tonsillar hypertrophy (enlargement of the tonsils)

20-29:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  4. Aortic valve incompetence
  5. Blood cholesterol increased
  6. Blood triglycerides increased
  7. Body temperature increased
  8. Chronic kidney disease
  9. Decreased appetite
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Osteoporosis (bones weak and more likely to break)
  5. Chronic kidney disease
  6. Fracture
  7. Lower limb fracture
  8. Multiple fractures
  9. Nightmare (unpleasant dream)

40-49:

  1. Depression
  2. Anxiety
  3. Chronic kidney disease
  4. Panic attack
  5. Renal failure (kidney dysfunction)
  6. Renal impairment (severely reduced kidney function)
  7. Drug hypersensitivity
  8. Drug ineffective
  9. Dyspnoea (difficult or laboured respiration)
  10. Gout (uric acid crystals building up in the body)

50-59:

  1. Facial pain
  2. Fracture
  3. Hip fracture
  4. Humerus fracture (injury to the upper arm bone)
  5. Hydrocephalus (water on the brain)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
  8. Lymphadenopathy (disease or enlargement of lymph nodes)
  9. Metastases to liver (cancer spreads to liver)
  10. Metastases to spine (cancer spreads to spine)

60+:

  1. Anaemia (lack of blood)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Cervix haemorrhage uterine (bleeding from cervix in birth canal)
  4. Disability
  5. Epicondylitis (tennis elbow)
  6. Herpes zoster
  7. Hypercholesterolaemia (high levels of cholesterol in the blood)
  8. Hypertension (high blood pressure)
  9. Injury
  10. Intervertebral disc degeneration (spinal disc degeneration)

What are the existing conditions these people have? *

  1. High Blood Pressure: 18 people, 23.38%
  2. High Blood Cholesterol: 14 people, 18.18%
  3. Hypercalcaemia (elevated calcium (ca+) level in the blood): 11 people, 14.29%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 14.29%
  5. Anaemia (lack of blood): 11 people, 14.29%
  6. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 11.69%
  7. Neoplasm Malignant (cancer tumour): 8 people, 10.39%
  8. Muscle Spasms (muscle contraction): 5 people, 6.49%
  9. Depression: 5 people, 6.49%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 5.19%

* Approximation only. Some reports may have incomplete information.

Do you take Ketoprofen and Cephalexin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ketoprofen and Cephalexin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ketoprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cephalexin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ketoprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cephalexin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ketoprofen and cephalexin (the active ingredients of Ketoprofen and Cephalexin, respectively), and Ketoprofen and Cephalexin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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