Ketoprofen and Sinemet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoprofen (ketoprofen) and Sinemet (carbidopa; levodopa). Common drug interactions include nasal septum ulceration among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoprofen and Sinemet. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoprofen?

Ketoprofen has active ingredients of ketoprofen. It is often used in pain. eHealthMe is studying from 15,048 Ketoprofen users. Check the latest studies of Ketoprofen.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

On Jul, 07, 2026

27 people who take Ketoprofen and Sinemet together, and have interactions are studied.

Ketoprofen and Sinemet drug interactions.

What are the common drug interactions of Ketoprofen and Sinemet, by gender? *:

female:

Nasal septum ulceration (ulcers on nasal septum)
Nausea (feeling of having an urge to vomit)
Nephritis (inflammation of the nephrons in the kidneys)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Oropharyngeal pain
Pruritus (severe itching of the skin)
Radicular pain (pain ""radiated"" along the dermatome (sensory distribution) of a nerve due to inflammation)
Respiratory distress (difficulty in breathing)
Rhinalgia (pain in the nose)
Skin discolouration (change of skin colour)

male:

Anaemia (lack of blood)
Cerebral haematoma (collection of blood in brain)
Abdominal distension
Abdominal pain
Bowel sounds
Constipation
Diarrhoea
Flatulence (flatus expelled through the anus)
Hypotension (abnormally low blood pressure)
Hypovolaemia (a decreased volume of circulating blood in the body)

What are the common drug interactions of Ketoprofen and Sinemet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Mitral valve disease (disease of mitral valve of heart)
Mitral valve disease mixed (disease process involving one or more of the valves of the heart)
Mitral valve replacement
Nasal discomfort
Nasal septum ulceration (ulcers on nasal septum)
Rhinalgia (pain in the nose)
Sleep phase rhythm disturbance (heart rate disturbances during sleep)
Acanthoma (a skin cancer)
Atrioventricular block complete (heart block complete)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

50-59:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood pressure decreased
Hepatitis (inflammation of the liver)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Hypersensitivity
Loss of consciousness
Nephritis (inflammation of the nephrons in the kidneys)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Radicular pain (pain ""radiated"" along the dermatome (sensory distribution) of a nerve due to inflammation)

60+:

Anaemia (lack of blood)
Constipation
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenic purpura (a bleeding disorder in which the immune system destroys platelets)
Cerebral haematoma (collection of blood in brain)
Dyspnoea (difficult or laboured respiration)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Psychomotor retardation (motor mental retardation)

What are the existing conditions these people have? *

Cardiac Failure: 4 people, 14.81%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 11.11%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Ketoprofen and Sinemet?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously