Keytruda and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keytruda (pembrolizumab) and Vancomycin (vancomycin). Common drug interactions include eosinophilia among females and delirium among males.

The phase IV clinical study analyzes what interactions people have when they take Keytruda and Vancomycin. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Keytruda?

Keytruda has active ingredients of pembrolizumab. It is often used in renal cell carcinoma. eHealthMe is studying from 57,404 Keytruda users. Check the latest studies of Keytruda.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

On Jul, 19, 2026

17 people who take Keytruda and Vancomycin together, and have interactions are studied.

Keytruda and Vancomycin drug interactions.

What are the common drug interactions of Keytruda and Vancomycin, by gender? *:

female:

Eosinophilia (eosinophil count in the peripheral blood exceeds)
Aspartate aminotransferase increased
Blood magnesium decreased
Blood potassium decreased
Blood sodium decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Feeling hot
Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Pyrexia (fever)

male:

Delirium (wild excitement)
Adverse drug reaction
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)
Blood pressure decreased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Cystitis (inflammation of the wall of the bladder)
Death
Dysphonia (speech disorder attributable to a disorder of phonation)
Fatigue (feeling of tiredness)
Joint swelling

What are the common drug interactions of Keytruda and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Eosinophilia (eosinophil count in the peripheral blood exceeds)
Feeling hot
Pyrexia (fever)
Rash

60+:

Aspartate aminotransferase increased
Delirium (wild excitement)
Dysphonia (speech disorder attributable to a disorder of phonation)
Fatigue (feeling of tiredness)
Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Joint swelling
Thyroid disorder (thyroid diseases)
Urinary tract infection
Adverse drug reaction

What are the existing conditions these people have? *

Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 6 people, 35.29%
Mediastinitis (inflammation of the tissues in the mid-chest): 6 people, 35.29%
Urinary Tract Infection: 2 people, 11.76%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 11.76%
Endometrial Cancer: 2 people, 11.76%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 11.76%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1 person, 5.88%
Aspartate Aminotransferase Increased: 1 person, 5.88%
Back Pain: 1 person, 5.88%
Constipation: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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