Kionex and Ursodiol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kionex (sodium polystyrene sulfonate) and Ursodiol (ursodiol). Common drug interactions include chronic kidney disease among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Kionex and Ursodiol. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Kionex?

Kionex has active ingredients of sodium polystyrene sulfonate. eHealthMe is studying from 478 Kionex users. Check the latest studies of Kionex.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

On Jul, 17, 2026

15 people who take Kionex and Ursodiol together, and have interactions are studied.

What are the common drug interactions of Kionex and Ursodiol, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal disorder (kidney disease)
Renal injury (kidney injury)
Abdominal distension
Chest pain
Death
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Hypoxia (low oxygen in tissues)

male:

Asthenia (weakness)
Blood pressure increased
Weight decreased
Gallbladder disorder
Chills (felling of cold)
Decreased appetite
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Frequent bowel movements

What are the common drug interactions of Kionex and Ursodiol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)

50-59:

n/a

60+:

Abdominal distension
Chest pain
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
Troponin increased
Death
Dyspnoea (difficult or laboured respiration)
Gallbladder disorder

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 53.33%
Pain: 8 people, 53.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 53.33%
Fungal Infection: 8 people, 53.33%
Indigestion: 7 people, 46.67%
Muscle Spasms (muscle contraction): 6 people, 40.00%
Hyperkalemia (damage to or disease of the kidney): 6 people, 40.00%
High Blood Cholesterol: 6 people, 40.00%
Gallstones (stone formation by bile component): 6 people, 40.00%
Blood Pressure Abnormal: 4 people, 26.67%

* Approximation only. Some reports may have incomplete information.

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