Klonopin and Ketamine hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Klonopin (clonazepam) and Ketamine hcl (ketamine hydrochloride). Common drug interactions include drug ineffective among females and disability among males.

The phase IV clinical study analyzes what interactions people have when they take Klonopin and Ketamine hcl. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

What is Ketamine hcl?

Ketamine hcl has active ingredients of ketamine hydrochloride. It is often used in pain. eHealthMe is studying from 1,851 Ketamine hcl users. Check the latest studies of Ketamine hcl.

On Jul, 15, 2026

15 people who take Klonopin and Ketamine hcl together, and have interactions are studied.

Klonopin and Ketamine hcl drug interactions.

What are the common drug interactions of Klonopin and Ketamine Hcl, by gender? *:

female:

Drug ineffective
Sleep attacks
Sleep paralysis (waking up and unable to move or speak)
Somnambulism (sleep walking)
Somnolence (a state of near-sleep, a strong desire for sleep)
Syncope (loss of consciousness with an inability to maintain postural tone)
Therapeutic response unexpected
Vitamin b12 decreased
Vitamin d deficiency
Agitation (state of anxiety or nervous excitement)

male:

Disability

What are the common drug interactions of Klonopin and Ketamine Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cerebrospinal fluid leakage
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Pseudomeningocele (abnormal collection of cerebrospinal fluid)
Swelling

30-39:

Fall
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Foot fracture
Ligament rupture (tear in ligament)
Memory impairment
Concussion (short loss of normal brain function in response to a head injury)
Hypervigilance

40-49:

Arthralgia (joint pain)
Blood potassium decreased
Fatigue (feeling of tiredness)
Foot ulcer
Gall bladder pain
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Joint dislocation (a joint position is changed from normal position)
Lethargy (tiredness)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 66.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 20.00%
Insomnia (sleeplessness): 2 people, 13.33%
Spinal Pain (pain in spine): 1 person, 6.67%
Sleep Disorder: 1 person, 6.67%
Drowsiness: 1 person, 6.67%
Constipation: 1 person, 6.67%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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