Klonopin and Lemtrada drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Klonopin (clonazepam) and Lemtrada (alemtuzumab). Common drug interactions include hyperthyroidism among females and insomnia among males.
The phase IV clinical study analyzes what interactions people have when they take Klonopin and Lemtrada. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Klonopin?
Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.
What is Lemtrada?
Lemtrada has active ingredients of alemtuzumab. eHealthMe is studying from 8,317 Lemtrada users. Check the latest studies of Lemtrada.
16 people who take Klonopin and Lemtrada together, and have interactions are studied.

What are the common drug interactions of Klonopin and Lemtrada, by gender? *:
female:
- Hyperthyroidism (over activity of the thyroid gland)
- Lymphocyte count increased
- Nausea (feeling of having an urge to vomit)
- Platelet count increased
- Temperature intolerance (inability to go in temperature)
- Thyroid disorder (thyroid diseases)
- Urinary sediment present
- Urine abnormality
- Urine leukocyte esterase positive
- Weight decreased
male:
- Insomnia (sleeplessness)
- Pyrexia (fever)
- Amylase increased
- Anger
- Blood chloride decreased
- Blood glucose increased
- Blood sodium decreased
- Blood urea decreased
- Bone pain
- Cardiomegaly (increased size of heart than normal)
What are the common drug interactions of Klonopin and Lemtrada, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Arthralgia (joint pain)
- Blood alkaline phosphatase increased
- Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
- Myalgia (muscle pain)
- Pyrexia (fever)
- Rash
- White blood cell disorder
- Anaemia (lack of blood)
- Pneumonia legionella (pneumonia caused by the bacteria legionella)
40-49:
- Herpes zoster
- Hypertension (high blood pressure)
- Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Fall
- Hand fracture
- Nausea (feeling of having an urge to vomit)
50-59:
- Crystal urine present
- Amylase increased
- Arthralgia (joint pain)
- Asthenia (weakness)
- Blood alkaline phosphatase increased
- Blood chloride decreased
- Blood glucose increased
- Blood sodium decreased
- Blood urea decreased
- Bone pain
60+:
- Gait disturbance
- Insomnia (sleeplessness)
- Decreased appetite
- Diarrhoea
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Ear infection
- Fall
- Fatigue (feeling of tiredness)
- Headache (pain in head)
What are the existing conditions these people have? *
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 37.50%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 37.50%
- Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 2 people, 12.50%
- Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 12.50%
- Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 2 people, 12.50%
- Gait Disturbance: 2 people, 12.50%
- Insomnia (sleeplessness): 1 person, 6.25%
- Bladder Disorder: 1 person, 6.25%
- Clonus (series of involuntary, rhythmic, muscular contractions and relaxations): 1 person, 6.25%
- Depression: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Klonopin and Lemtrada?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Klonopin and Lemtrada:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Klonopin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lemtrada:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Klonopin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lemtrada and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clonazepam and alemtuzumab (the active ingredients of Klonopin and Lemtrada, respectively), and Klonopin and Lemtrada (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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