Klonopin and Macitentan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Klonopin (clonazepam) and Macitentan (macitentan). Common drug interactions include pneumonia among females.
The phase IV clinical study analyzes what interactions people have when they take Klonopin and Macitentan. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Klonopin?
Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.
What is Macitentan?
Macitentan has active ingredients of macitentan. eHealthMe is studying from 7,371 Macitentan users. Check the latest studies of Macitentan.
12 people who take Klonopin and Macitentan together, and have interactions are studied.
What are the common drug interactions of Klonopin and Macitentan, by gender? *:
female:
- Pneumonia
- Blood pressure increased
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
- Pyrexia (fever)
- Respiratory distress (difficulty in breathing)
- Septic shock (shock due to blood infection)
- Swelling
- Systolic hypertension (an elevated systolic blood pressure)
- Weight decreased
- Abdominal pain
male:
n/a
What are the common drug interactions of Klonopin and Macitentan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Swelling
- Cardiac failure congestive
- Erythema (redness of the skin)
- Pain
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
- Pyrexia (fever)
- Subcutaneous abscess
50-59:
- Abdominal pain
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Nausea (feeling of having an urge to vomit)
- Oedema (fluid collection in tissue)
- Oxygen saturation decreased
- Pleural effusion (water on the lungs)
- Pulmonary oedema (fluid accumulation in the lungs)
60+:
- Pneumonia
- Blood pressure increased
- Dysstasia (difficulty in standing)
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
- Enzyme abnormality
- Haemoglobin decreased
- Herpes zoster
- Influenza
- Influenza like illness
- Malaise (a feeling of general discomfort or uneasiness)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 12 people, 100.00%
* Approximation only. Some reports may have incomplete information.
Do you take Klonopin and Macitentan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Klonopin (65,112 reports)
- Macitentan (7,371 reports)
Browse all drug interactions of Klonopin and Macitentan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Klonopin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Macitentan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Klonopin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Macitentan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clonazepam and macitentan (the active ingredients of Klonopin and Macitentan, respectively), and Klonopin and Macitentan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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