Klonopin and Sprix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Klonopin (clonazepam) and Sprix (ketorolac tromethamine). Common drug interactions include facial paralysis among females.
The phase IV clinical study analyzes what interactions people have when they take Klonopin and Sprix. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Klonopin?
Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.
What is Sprix?
Sprix has active ingredients of ketorolac tromethamine. eHealthMe is studying from 616 Sprix users. Check the latest studies of Sprix.
14 people who take Klonopin and Sprix together, and have interactions are studied.
What are the common drug interactions of Klonopin and Sprix, by gender? *:
female:
- Facial paralysis (loss of function of face muscle)
- Surgery
- Drug intolerance (drug sensitivity)
- Dry eye (lack of adequate tears)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Emotional disorder
- Fatigue (feeling of tiredness)
- Head injury
- Hypoglycaemia (deficiency of glucose in the bloodstream)
male:
n/a
What are the common drug interactions of Klonopin and Sprix, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Nasal discomfort
- Retching (strong involuntary effort to vomit)
- Rhinorrhoea (watery mucus discharge from the nose)
- Rotator cuff repair
- Sleep disorder
- Adjustment disorder with depressed mood
- Cellulitis (infection under the skin)
- Dehydration (dryness resulting from the removal of water)
- Dysphagia (a condition in which swallowing is difficult or painful)
50-59:
n/a
60+:
- Decreased interest
- Depressed mood
- Depression
- Pneumonia
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 64.29%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 57.14%
- Sleep Disorder: 1 person, 7.14%
- Pain: 1 person, 7.14%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
- Migraine (headache): 1 person, 7.14%
- Headache (pain in head): 1 person, 7.14%
- Gout (uric acid crystals building up in the body): 1 person, 7.14%
- Drowsiness: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Klonopin and Sprix?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Klonopin and Sprix:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Klonopin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sprix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Klonopin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sprix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clonazepam and ketorolac tromethamine (the active ingredients of Klonopin and Sprix, respectively), and Klonopin and Sprix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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