Korlym and Lamotrigine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Korlym (mifepristone) and Lamotrigine (lamotrigine). Common drug interactions include fatigue among females and nausea among males.
The phase IV clinical study analyzes what interactions people have when they take Korlym and Lamotrigine. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Korlym?
Korlym has active ingredients of mifepristone. eHealthMe is studying from 3,078 Korlym users. Check the latest studies of Korlym.
What is Lamotrigine?
Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.
20 people who take Korlym and Lamotrigine together, and have interactions are studied.

What are the common drug interactions of Korlym and Lamotrigine, by gender? *:
female:
- Fatigue (feeling of tiredness)
- Acne (skin problems that cause pimples)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Blood thyroid stimulating hormone increased
- Blood triglycerides increased
- Diarrhoea
- Emotional disorder
- Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
- Nasopharyngitis (inflammation of the nasopharynx)
- Skin ulcer
male:
- Nausea (feeling of having an urge to vomit)
- Nephrolithiasis (calculi in the kidneys)
- Bacterial infection
- Blood glucose increased
- Blood sodium decreased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Diarrhoea
- Flatulence (flatus expelled through the anus)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Myalgia (muscle pain)
What are the common drug interactions of Korlym and Lamotrigine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Burning sensation
- Hypoaesthesia (reduced sense of touch or sensation)
- Nausea (feeling of having an urge to vomit)
- Nephrolithiasis (calculi in the kidneys)
- Pain of skin
40-49:
n/a
50-59:
- Fatigue (feeling of tiredness)
- Arthralgia (joint pain)
- Bacterial infection
- Blood glucose decreased
- Blood glucose increased
- Blood sodium decreased
- Myalgia (muscle pain)
- Nausea (feeling of having an urge to vomit)
- Pain in extremity
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
60+:
- Abdominal pain
- Blood glucose decreased
- Oral mucosal eruption (a sudden appearing of rash on mucous membrane of mouth)
- Vomiting
- Chills (felling of cold)
- Dizziness
- Dyspnoea exertional (breathlessness or shortness of breath)
- Fatigue (feeling of tiredness)
- Gallbladder disorder
- Influenza
What are the existing conditions these people have? *
- Cushing's Syndrome (obesity, a rounded face, increased fat): 17 people, 85.00%
- Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 2 people, 10.00%
- Joint Pain: 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Korlym and Lamotrigine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Korlym (3,078 reports)
- Lamotrigine (76,638 reports)
Browse all drug interactions of Korlym and Lamotrigine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Korlym:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lamotrigine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Korlym and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lamotrigine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on mifepristone and lamotrigine (the active ingredients of Korlym and Lamotrigine, respectively), and Korlym and Lamotrigine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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