Kyprolis and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kyprolis (carfilzomib) and Ibu (ibuprofen). Common drug interactions include chronic kidney disease among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Kyprolis and Ibu. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Kyprolis?

Kyprolis has active ingredients of carfilzomib. It is often used in multiple myeloma. eHealthMe is studying from 15,080 Kyprolis users. Check the latest studies of Kyprolis.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

On Aug, 07, 2026

74 people who take Kyprolis and Ibu together, and have interactions are studied.

What are the common drug interactions of Kyprolis and Ibu, by gender? *:

female:

Chronic kidney disease
Colitis (inflammation of colon)
Constipation
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Rectal haemorrhage (bleeding from anus)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Urticaria (rash of round, red welts on the skin that itch intensely)
Drug administration error
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

male:

Pneumonia
Diarrhoea
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bradycardia (abnormally slow heart action)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Disease progression
Dry skin

What are the common drug interactions of Kyprolis and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Disease progression
Syncope (loss of consciousness with an inability to maintain postural tone)

40-49:

Rash macular (small, flat red spots)
Rash pruritic (redness with itching)
Urticaria (rash of round, red welts on the skin that itch intensely)
Pyrexia (fever)

50-59:

Febrile neutropenia (fever with reduced white blood cells)
Pneumonia
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pyrexia (fever)
Rash
Septic shock (shock due to blood infection)

60+:

Diarrhoea
Platelet count decreased
Colitis (inflammation of colon)
Fatigue (feeling of tiredness)
Leukopenia (less number of white blood cells in blood)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Rectal haemorrhage (bleeding from anus)
Thrombocytopenia (decrease of platelets in blood)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the existing conditions these people have? *

Neuropathy Peripheral (surface nerve damage): 4 people, 5.41%
High Blood Pressure: 4 people, 5.41%
Diabetes: 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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