Kytril and Vistaril drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Kytril (granisetron hydrochloride) and Vistaril (hydroxyzine hydrochloride). Common drug interactions include metastases to eye among females and seizure among males.
The phase IV clinical study analyzes what interactions people have when they take Kytril and Vistaril. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Kytril?
Kytril has active ingredients of granisetron hydrochloride. eHealthMe is studying from 10,766 Kytril users. Check the latest studies of Kytril.
What is Vistaril?
Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.
16 people who take Kytril and Vistaril together, and have interactions are studied.

What are the common drug interactions of Kytril and Vistaril, by gender? *:
female:
- Metastases to eye (cancer spreads to eye)
- Metastases to stomach (cancer spreads to stomach)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pain in extremity
- Periodontal disease (disease that attacks the gum and bone and around the teeth)
- Sensitivity of teeth
- Sinus disorder (disease of sinus)
- Swelling
- Vena cava injury
- Diarrhoea
male:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Drug hypersensitivity
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Blood follicle stimulating hormone increased
- Blood glucose increased
- Bone disorder
- Breast cancer metastatic
- Carbohydrate antigen 27.29 increased
- Coma (state of unconsciousness lasting more than six hours)
What are the common drug interactions of Kytril and Vistaril, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Headache (pain in head)
- Pyrexia (fever)
10-19:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Headache (pain in head)
- Abdominal pain
- Abdominal pain upper
- Alveolar osteitis (complication of wound healing following extraction of a tooth)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Asthenia (weakness)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Osteomyelitis (infection of bone)
- Osteonecrosis of jaw (death of bone of jaw)
- Pain in jaw
- Pleural effusion (water on the lungs)
- Pneumonia
- Renal failure acute (rapid kidney dysfunction)
- Restlessness (not able to rest)
- Alopecia (absence of hair from areas of the body)
- Breast cancer metastatic
- Depression
60+:
- Drug hypersensitivity
- Abdominal pain
- Bone disorder
- Cyst (a closed sac)
- Dementia (madness)
- Depression
- Disease progression
- Dysgeusia (disorder of the sense of taste)
- Dyspnoea (difficult or laboured respiration)
- Fall
What are the existing conditions these people have? *
- Breast Cancer: 6 people, 37.50%
- Nervous System Disorder (a general class of medical conditions affecting the nervous system): 5 people, 31.25%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 25.00%
- Nausea And Vomiting: 4 people, 25.00%
- Metastases To Bone (cancer spreads to bone): 4 people, 25.00%
- Depression: 4 people, 25.00%
- Indigestion: 3 people, 18.75%
- Constipation: 3 people, 18.75%
- Pain: 3 people, 18.75%
- Nausea (feeling of having an urge to vomit): 3 people, 18.75%
* Approximation only. Some reports may have incomplete information.
Do you take Kytril and Vistaril?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Kytril and Vistaril:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Kytril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vistaril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Kytril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vistaril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on granisetron hydrochloride and hydroxyzine hydrochloride (the active ingredients of Kytril and Vistaril, respectively), and Kytril and Vistaril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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