L-lysine and Folate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take L-lysine (lysine) and Folate (folic acid). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take L-lysine and Folate. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is L-lysine?

L-lysine has active ingredients of lysine. It is often used in herpes labialis (oral herpes simplex). eHealthMe is studying from 1,560 L-lysine users. Check the latest studies of L-lysine.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.

On Jul, 18, 2026

14 people who take L-lysine and Folate together, and have interactions are studied.

What are the common drug interactions of L-Lysine and Folate, by gender? *:

female:

Fatigue (feeling of tiredness)
Anxiety
Rhinorrhoea (watery mucus discharge from the nose)
Suicidal ideation
Accident at home
Acute respiratory failure
Adverse event
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Crying

male:

n/a

What are the common drug interactions of L-Lysine and Folate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Dissociation
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Panic attack

30-39:

n/a

40-49:

n/a

50-59:

Chondropathy (disease of the cartilage)
Drug ineffective
Pulmonary thrombosis (scarring in the lungs)
Suicidal ideation
Acute respiratory failure
Intervertebral disc protrusion (spinal disc protrusion)
Knee arthroplasty
Shoulder operation

60+:

Fatigue (feeling of tiredness)
Accident at home
Malaise (a feeling of general discomfort or uneasiness)
Oropharyngeal pain
Pain
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Weight fluctuation
Anxiety
Crying
Disease recurrence

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 28.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
Stress And Anxiety: 3 people, 21.43%
Depression: 3 people, 21.43%
Pain: 3 people, 21.43%
Neuropathy Peripheral (surface nerve damage): 3 people, 21.43%
Diabetes: 3 people, 21.43%
Asthma: 2 people, 14.29%
Back Pain: 2 people, 14.29%
Urinary Tract Infection: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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