Lacosamide and Decadron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lacosamide (lacosamide) and Decadron (dexamethasone). Common drug interactions include sensitivity of teeth among females and delirium among males.

The phase IV clinical study analyzes what interactions people have when they take Lacosamide and Decadron. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

What is Decadron?

Decadron has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 47,210 Decadron users. Check the latest studies of Decadron.



On Jul, 09, 2026

44 people who take Lacosamide and Decadron together, and have interactions are studied.

Lacosamide and Decadron drug interactions.

What are the common drug interactions of Lacosamide and Decadron, by gender? *:

female:

  1. Sensitivity of teeth
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Small intestinal perforation (hole in small intestine)
  4. Depression
  5. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  7. Dizziness
  8. Malignant neoplasm progression (cancer tumour came back)
  9. Asthenia (weakness)
  10. Erythema (redness of the skin)

male:

  1. Delirium (wild excitement)
  2. Confusional state
  3. Cancer pain
  4. Dehydration (dryness resulting from the removal of water)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Fatigue (feeling of tiredness)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Overdose
  9. Stomatitis (inflammation of mucous membrane of mouth)
  10. Metastases to bone (cancer spreads to bone)

What are the common drug interactions of Lacosamide and Decadron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blood glucose increased
  2. Mood swings (an extreme or rapid change in mood)
  3. Weight increased
  4. Device failure
  5. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  6. Partial seizures (seizures which affect only a part of the brain at onset)
  7. Drug ineffective

30-39:

  1. Death
  2. Asthenia (weakness)
  3. Fall
  4. Performance status decreased

40-49:

  1. Asthenia (weakness)
  2. Confusional state
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults)
  5. Oedema (fluid collection in tissue)
  6. Overdose
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Weight decreased
  9. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  10. Rash

50-59:

  1. Constipation
  2. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  3. Death
  4. Fatigue (feeling of tiredness)
  5. Altered state of consciousness (altered state of mind)
  6. Cancer pain
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  8. Dehydration (dryness resulting from the removal of water)
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults)

60+:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Delirium (wild excitement)
  3. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  4. Decreased appetite
  5. Dizziness
  6. Dry gangrene (diminished blood supply due to vascular problems)
  7. Gait disturbance
  8. Headache (pain in head)
  9. Infusion related reaction
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 13.64%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 6 people, 13.64%
  3. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 11.36%
  4. Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 5 people, 11.36%
  5. Simple Partial Seizures (seizures which affect only a small region of the brain): 4 people, 9.09%
  6. Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Lacosamide and Decadron?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lacosamide and Decadron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lacosamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Decadron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lacosamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Decadron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lacosamide and dexamethasone (the active ingredients of Lacosamide and Decadron, respectively), and Lacosamide and Decadron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: