Lacosamide and Lortab drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lacosamide (lacosamide) and Lortab (acetaminophen; hydrocodone bitartrate). Common drug interactions include oedema peripheral among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Lacosamide and Lortab. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

On Jul, 12, 2026

14 people who take Lacosamide and Lortab together, and have interactions are studied.

Lacosamide and Lortab drug interactions.

What are the common drug interactions of Lacosamide and Lortab, by gender? *:

female:

Oedema peripheral (superficial swelling)
Chest discomfort
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Abdominal pain
Abdominal pain lower
Anxiety
Apallic syndrome (serious brain damage, when cortical parts of the brain are disconnected from brainstem)
Apnoeic attack
Atrial thrombosis (blood clot that develops in an artery)

male:

Dizziness
Epistaxis (bleed from the nose)
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary tract infection
Cardiac murmur (an heart sound in valve abnormality)
Chest pain
Dermatitis diaper (diaper rash is a common form of inflamed skin)
Eczema infected (eczema due to bacterial infection or with bacterial infection)
Immature respiratory system
Jaundice neonatal (yellowing of skin in neonate)

What are the common drug interactions of Lacosamide and Lortab, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Apallic syndrome (serious brain damage, when cortical parts of the brain are disconnected from brainstem)
Apnoeic attack
Atrial thrombosis (blood clot that develops in an artery)
Bedridden
Brain hypoxia (reduced supply of oxygen to the brain)
Brain injury
Cardiac arrest
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cerebral thrombosis (blood clot in brain)

30-39:

Chest pain
Dizziness
Vision blurred

40-49:

Abdominal pain upper
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug ineffective
Loss of consciousness

50-59:

Abdominal pain
Dizziness
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)

60+:

Oedema peripheral (superficial swelling)
Chest discomfort
Dry skin
Fall
Head injury
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Joint swelling
Limb injury
Muscular weakness (muscle weakness)

What are the existing conditions these people have? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 35.71%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 28.57%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 21.43%
Acne (skin problems that cause pimples): 2 people, 14.29%
Embolism Venous (embolus may pass into the arterial system): 2 people, 14.29%
Inflammation: 2 people, 14.29%
Impaired Gastric Emptying: 2 people, 14.29%
Skin Disorder (skin disease): 2 people, 14.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.14%
Depression: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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