Lactobacillus and Truvada drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lactobacillus (lactobacillus) and Truvada (emtricitabine; tenofovir disoproxil fumarate). Common drug interactions include emotional distress among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Lactobacillus and Truvada. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lactobacillus?

Lactobacillus has active ingredients of lactobacillus. It is often used in stomach discomfort. eHealthMe is studying from 5,854 Lactobacillus users. Check the latest studies of Lactobacillus.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

18 people who take Lactobacillus and Truvada together, and have interactions are studied.

Lactobacillus and Truvada drug interactions.

What are the common drug interactions of Lactobacillus and Truvada, by gender? *:

female:

Emotional distress
Osteoporosis (bones weak and more likely to break)
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthropathy
Bone density decreased
Gait disturbance
Mobility decreased (ability to move is reduced)
Chronic kidney disease

male:

Emotional distress
Pain
Renal impairment (severely reduced kidney function)
Generalised oedema (swelling all over the body)
Hypertension (high blood pressure)
Lip swelling
Nephropathy (damage to or disease of a kidney)
Pruritus (severe itching of the skin)
Swelling
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the common drug interactions of Lactobacillus and Truvada, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal distension
Atrioventricular block second degree (heart block second degree)
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Campylobacter gastroenteritis (infection of gastrointestinal system)
Dyslipidaemia (abnormal amount of lipids)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemoglobin decreased
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Herpes zoster

30-39:

Emotional distress
Pain
Bone density decreased
Anxiety
Renal failure (kidney dysfunction)
Chronic kidney disease
Nephropathy (damage to or disease of a kidney)
Tooth loss
Abnormal dreams
Bone loss

40-49:

Hypersensitivity
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthropathy
Bone density decreased
Emotional distress
Gait disturbance
Generalised oedema (swelling all over the body)
Hypertension (high blood pressure)
Lip swelling

50-59:

Chronic kidney disease
Emotional distress
Pain
Renal impairment (severely reduced kidney function)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Osteoporosis (bones weak and more likely to break)
Pain
Spinal fracture (fracture in one of vertebrae)

What are the existing conditions these people have? *

Pain: 9 people, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 27.78%
Dyslipidaemia (abnormal amount of lipids): 4 people, 22.22%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 22.22%
High Blood Cholesterol: 4 people, 22.22%
Hypersensitivity: 4 people, 22.22%
High Blood Pressure: 3 people, 16.67%
Nausea (feeling of having an urge to vomit): 3 people, 16.67%
Depression: 3 people, 16.67%
Insomnia (sleeplessness): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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