Lactulose and Nicorette drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lactulose (lactulose) and Nicorette (nicotine polacrilex). Common drug interactions include weight increased among females and neoplasm malignant among males.

The phase IV clinical study analyzes what interactions people have when they take Lactulose and Nicorette. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

What is Nicorette?

Nicorette has active ingredients of nicotine polacrilex. It is often used in quit smoking. eHealthMe is studying from 18,484 Nicorette users. Check the latest studies of Nicorette.

On Jul, 30, 2026

42 people who take Lactulose and Nicorette together, and have interactions are studied.

Lactulose and Nicorette drug interactions.

What are the common drug interactions of Lactulose and Nicorette, by gender? *:

female:

Weight increased
Arthralgia (joint pain)
Back pain
Headache (pain in head)
Oedema peripheral (superficial swelling)
Pain
Rash
Skin infection
Abscess oral (abscess in the mouth)
Eosinophil count decreased

male:

Neoplasm malignant (cancer tumour)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Renal failure acute (rapid kidney dysfunction)
Swollen tongue (swelling of tongue)

What are the common drug interactions of Lactulose and Nicorette, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Eosinophil count decreased
Haemoglobin decreased
Haemorrhage (bleeding)
Intentional self-injury
Mean cell haemoglobin concentration decreased (less concentration of haemoglobin in a given volume of packed red blood cells)
Mean cell volume increased (more than normal average red blood cell volume)
Red blood cell count decreased
Arthralgia (joint pain)
Blood alkaline phosphatase increased
Drug exposure during pregnancy

30-39:

Drug screen false positive

40-49:

Pickwickian syndrome (extreme obesity accompanied by sleepiness, hypoventilation, and polycythemia)
Dyspnoea (difficult or laboured respiration)
Weight increased
Asthma

50-59:

Impaired gastric emptying
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anaemia (lack of blood)
Back pain
Depression
Gun shot wound
Hospitalisation
Hot flush (sudden feelings of heat)
Hypokalaemia (low potassium)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Neoplasm malignant (cancer tumour)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
Oesophagitis (inflammation of oesophagus)
Renal failure acute (rapid kidney dysfunction)
Osteonecrosis of jaw (death of bone of jaw)
Postoperative wound complication
Abscess oral (abscess in the mouth)
Mouth ulceration (mouth ulcers)
Chest discomfort

What are the existing conditions these people have? *

Agitation (state of anxiety or nervous excitement): 15 people, 35.71%
Pain: 14 people, 33.33%
Stress And Anxiety: 11 people, 26.19%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 11 people, 26.19%
Depressive Symptom: 11 people, 26.19%
Affective Disorder (mental disorder): 11 people, 26.19%
Irritable Bowel Syndrome: 11 people, 26.19%
Depression: 9 people, 21.43%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 8 people, 19.05%
Insomnia (sleeplessness): 7 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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