Lactulose and Tekturna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lactulose (lactulose) and Tekturna (aliskiren hemifumarate). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Lactulose and Tekturna. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

18 people who take Lactulose and Tekturna together, and have interactions are studied.

Lactulose and Tekturna drug interactions.

What are the common drug interactions of Lactulose and Tekturna, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Emotional disorder
Fatigue (feeling of tiredness)
Respiratory distress (difficulty in breathing)
Restless legs syndrome (a powerful urge to move your legs)
Tardive dyskinesia (a disorder that involves involuntary movements)
Abdominal distension
Abdominal pain
Abdominal tenderness

male:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Vomiting
Renal failure (kidney dysfunction)
Acute myocardial infarction (acute heart attack)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Phlebitis (inflammation of the walls of a vein)
Pleural effusion (water on the lungs)

What are the common drug interactions of Lactulose and Tekturna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal injury (kidney injury)

40-49:

Chronic kidney disease

50-59:

Pleural effusion (water on the lungs)
Renal failure (kidney dysfunction)
Chest pain
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)

60+:

Chronic kidney disease
Emotional disorder
Blood urine present
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death
Dry mouth
Dysuria (painful or difficult urination)
Eye disorder
Fatigue (feeling of tiredness)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 44.44%
Stress And Anxiety: 6 people, 33.33%
Diabetes: 6 people, 33.33%
High Blood Cholesterol: 5 people, 27.78%
Infection: 5 people, 27.78%
Hypersensitivity: 4 people, 22.22%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 22.22%
Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 22.22%
Migraine (headache): 4 people, 22.22%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

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