Lamisil and Hyzaar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamisil (terbinafine hydrochloride) and Hyzaar (hydrochlorothiazide; losartan potassium). Common drug interactions include atrial fibrillation among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Lamisil and Hyzaar. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

What is Hyzaar?

Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 16,614 Hyzaar users. Check the latest studies of Hyzaar.

On Jul, 11, 2026

57 people who take Lamisil and Hyzaar together, and have interactions are studied.

What are the common drug interactions of Lamisil and Hyzaar, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Breast lump (localized swelling that feels different from the surrounding breast tissue)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cerebral oedema (swelling of brain)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Chronic kidney disease
Confusion
Cough
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Diabetes mellitus inadequate control

male:

Cardiac failure congestive
Alanine aminotransferase increased
Pneumonia
Rash
Renal failure (kidney dysfunction)
Weight decreased
Arrhythmia (irregular heartbeat)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the common drug interactions of Lamisil and Hyzaar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Adverse event

40-49:

Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Breast lump (localized swelling that feels different from the surrounding breast tissue)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cough
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diarrhoea
Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Mitral valve incompetence (inefficient heart valve)

50-59:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cerebellar infarction (impaired blood circulation to cerebellum)
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
Cerebral artery stenosis (hardening of brain blood vessels)
Cerebral ventricle dilatation (enlargement of ventricle of brain)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Clumsiness (a lack of coordination or elegance)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

60+:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Cardiac failure congestive
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Chest pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness
Dyspepsia (indigestion)
Fluid overload (too much fluid in the blood)
Haematocrit decreased

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 10 people, 17.54%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 12.28%
Diabetes: 7 people, 12.28%
High Blood Cholesterol: 6 people, 10.53%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 8.77%
Fungal Nail Infection: 5 people, 8.77%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 7.02%
Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 7.02%
Joint Pain: 4 people, 7.02%
Headache (pain in head): 4 people, 7.02%

* Approximation only. Some reports may have incomplete information.

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