Lamisil and Lamotrigine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamisil (terbinafine hydrochloride) and Lamotrigine (lamotrigine). Common drug interactions include erythema among females and appendicitis among males.

The phase IV clinical study analyzes what interactions people have when they take Lamisil and Lamotrigine. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

On Jul, 12, 2026

37 people who take Lamisil and Lamotrigine together, and have interactions are studied.

Lamisil and Lamotrigine drug interactions.

What are the common drug interactions of Lamisil and Lamotrigine, by gender? *:

female:

Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Photosensitivity reaction
Solar dermatitis (a condition in which a person develops a rash after exposure to sunlight)
Rash
Pyrexia (fever)
Alanine aminotransferase increased
C-reactive protein increased
Conjunctivitis (pink eye)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

male:

Appendicitis (inflammation of the appendix)
Arthralgia (joint pain)
Hypertension (high blood pressure)
Hypertrophic cardiomyopathy (a condition in which the heart muscle becomes abnormally thick)
Intervertebral disc disorder (spinal disc disorder)
Memory impairment
Overdose
Road traffic accident
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sinusitis (inflammation of sinus)

What are the common drug interactions of Lamisil and Lamotrigine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Conjunctival hyperaemia (congestion of conjunctival vessels)
Dacryostenosis acquired (obstruction of the nasolacrimal duct-acquired)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Pain
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash
Rash erythematous (redness of the skin)

20-29:

Erythema (redness of the skin)
Photosensitivity reaction
Pruritus (severe itching of the skin)
Solar dermatitis (a condition in which a person develops a rash after exposure to sunlight)
Rash pruritic (redness with itching)

30-39:

Discomfort
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Rash
Sleep disorder
Pruritus (severe itching of the skin)
Scab (a hard coating on the skin formed during the wound healing)
Skin swelling
Face oedema (swelling of face)
Generalised erythema (redness of the skin all over the body)
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Fatigue (feeling of tiredness)
Headache (pain in head)
Lymphadenopathy (disease or enlargement of lymph nodes)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Rash

50-59:

Oculomucocutaneous syndrome (a condition characterized by keratoconjunctivitis sicca and by scarring, fibrosis, metaplasia, and shrinkage of the conjunctiva;)
Oral mucosal eruption (a sudden appearing of rash on mucous membrane of mouth)
Pyrexia (fever)
Rash
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Stomatitis (inflammation of mucous membrane of mouth)
Somnolence (a state of near-sleep, a strong desire for sleep)
Sedation
Headache (pain in head)
Alanine aminotransferase increased

60+:

Disease recurrence
Sedation

What are the existing conditions these people have? *

Insomnia (sleeplessness): 11 people, 29.73%
Fungal Nail Infection: 10 people, 27.03%
Fungal Skin Infection: 9 people, 24.32%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 8.11%
Constipation: 3 people, 8.11%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 3 people, 8.11%
Fungal Infection: 3 people, 8.11%
Affective Disorder (mental disorder): 3 people, 8.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.11%
Psychotic Disorder: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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