Lamisil and Rezulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamisil (terbinafine hydrochloride) and Rezulin (troglitazone). Common drug interactions include diarrhoea among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Lamisil and Rezulin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

What is Rezulin?

Rezulin has active ingredients of troglitazone. eHealthMe is studying from 8,764 Rezulin users. Check the latest studies of Rezulin.



On Jul, 11, 2026

18 people who take Lamisil and Rezulin together, and have interactions are studied.

Lamisil and Rezulin drug interactions.

What are the common drug interactions of Lamisil and Rezulin, by gender? *:

female:

  1. Diarrhoea
  2. Bradycardia (abnormally slow heart action)
  3. Cardiac failure
  4. Cardiac failure congestive
  5. Coma (state of unconsciousness lasting more than six hours)
  6. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  7. Dyspnoea (difficult or laboured respiration)
  8. Fluid retention (an abnormal accumulation of fluid in the blood)
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Hypotension (abnormally low blood pressure)

male:

  1. Chronic kidney disease
  2. Diabetic end stage renal disease
  3. Obesity (having too much body fat)
  4. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Type 2 diabetes mellitus
  7. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  8. Cardiac failure congestive
  9. Chronic fatigue syndrome (disorder that causes extreme fatigue)
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Lamisil and Rezulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Drug effect decreased

10-19:

n/a

20-29:

n/a

30-39:

  1. Extrasystoles
  2. Fatigue (feeling of tiredness)
  3. Oedema peripheral (superficial swelling)

40-49:

  1. Breast lump (localized swelling that feels different from the surrounding breast tissue)
  2. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  3. Cough
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Diabetes mellitus inadequate control
  6. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  7. Diarrhoea
  8. Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Mitral valve incompetence (inefficient heart valve)
  10. Nasopharyngitis (inflammation of the nasopharynx)

50-59:

  1. Chronic kidney disease
  2. Diabetic end stage renal disease
  3. Drug ineffective
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Renal failure (kidney dysfunction)
  7. Renal injury (kidney injury)
  8. Cardiac failure congestive
  9. Chronic fatigue syndrome (disorder that causes extreme fatigue)
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Weight increased
  2. Bradycardia (abnormally slow heart action)
  3. Nausea (feeling of having an urge to vomit)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Sudden death unexplained
  6. Acute pre-renal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
  7. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  8. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  9. Atrophy (wasting away of a part of the body)
  10. Blood magnesium decreased

What are the existing conditions these people have? *

  1. Swelling: 4 people, 22.22%
  2. Pain: 4 people, 22.22%
  3. Neuropathy Peripheral (surface nerve damage): 4 people, 22.22%
  4. Kidney Stones: 4 people, 22.22%
  5. Inflammation: 4 people, 22.22%
  6. Hypersensitivity: 4 people, 22.22%
  7. High Blood Pressure: 4 people, 22.22%
  8. High Blood Cholesterol: 4 people, 22.22%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 22.22%
  10. Diabetes: 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

Do you take Lamisil and Rezulin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamisil and Rezulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamisil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rezulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamisil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rezulin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on terbinafine hydrochloride and troglitazone (the active ingredients of Lamisil and Rezulin, respectively), and Lamisil and Rezulin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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