Lamotrigine and Aricept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Aricept (donepezil hydrochloride). Common drug interactions include headache among females and somnolence among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Aricept. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

On Jul, 04, 2026

97 people who take Lamotrigine and Aricept together, and have interactions are studied.

Lamotrigine and Aricept drug interactions.

What are the common drug interactions of Lamotrigine and Aricept, by gender? *:

female:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Anxiety
Pain
Blood pressure increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Gait disturbance
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)

male:

Somnolence (a state of near-sleep, a strong desire for sleep)
Hallucination (an experience involving the perception of something not present)
Dizziness
Drug hypersensitivity
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
Neoplasm malignant (cancer tumour)
Vision blurred
Depression
Gait disturbance

What are the common drug interactions of Lamotrigine and Aricept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hypotension (abnormally low blood pressure)
Asthenia (weakness)
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Gait disturbance
Incoherent (talking in a confused and unclear way)
Pyrexia (fever)
Subdural effusion (collection of fluid trapped between the surface of the brain and the outer lining of the brain)
Syncope (loss of consciousness with an inability to maintain postural tone)

50-59:

Arthralgia (joint pain)
Asthenia (weakness)
Blood viscosity increased
Breast cancer
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depression
Dizziness
Drug hypersensitivity
Granulocytopenia (lack of granulocyte)
Hordeolum (small collection of pus (abscess) on the eyelid)

60+:

Somnolence (a state of near-sleep, a strong desire for sleep)
Hallucination (an experience involving the perception of something not present)
Gait disturbance
Aphasia (damage to the parts of the brain that control language)
Cerebral arteriosclerosis (thickening and hardening of the walls of the arteries in the brain)
Drug hypersensitivity
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
Neoplasm malignant (cancer tumour)
Vision blurred

What are the existing conditions these people have? *

Insomnia (sleeplessness): 18 people, 18.56%
Pain: 15 people, 15.46%
Depression: 13 people, 13.40%
High Blood Pressure: 12 people, 12.37%
Memory Loss: 11 people, 11.34%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 10 people, 10.31%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 10.31%
High Blood Cholesterol: 9 people, 9.28%
Blood Pressure Abnormal: 8 people, 8.25%
Cardiac Disorder: 8 people, 8.25%

* Approximation only. Some reports may have incomplete information.

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