Lamotrigine and Avapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Avapro (irbesartan). Common drug interactions include back injury among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Avapro. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

On Aug, 08, 2026

11 people who take Lamotrigine and Avapro together, and have interactions are studied.

Lamotrigine and Avapro drug interactions.

What are the common drug interactions of Lamotrigine and Avapro, by gender? *:

female:

Back injury
Blood creatinine increased
Blood magnesium decreased
Confusional state
Depressed mood
Diarrhoea
Face oedema (swelling of face)
Glossodynia (a burning or painful sensation in the tongue)
Haematocrit decreased
Haemoglobin decreased

male:

Nausea (feeling of having an urge to vomit)
Abdominal distension
Drug effect decreased
Fatigue (feeling of tiredness)
Heart rate decreased
Hot flush (sudden feelings of heat)
Intestinal obstruction
Muscular weakness (muscle weakness)
Pain
Pneumonia

What are the common drug interactions of Lamotrigine and Avapro, by age (0-1 to 60+)? *:

0-1:

Dizziness
Foetal distress syndrome (altered heart rate or rhythm and leading tocompromised blood flow or changes in blood chemistry of foetus)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Haemorrhage (bleeding)

2-9:

n/a

10-19:

n/a

20-29:

Abdominal distension
Abdominal infection
Abdominal pain
Abdominal pain lower
Blood pressure decreased
Blood pressure systolic increased
Cough
Decreased appetite
Diarrhoea
Drug effect decreased

30-39:

n/a

40-49:

Diarrhoea
Face oedema (swelling of face)
Headache (pain in head)

50-59:

Local swelling (swelling at the site of some application of substance or injury)
Loss of consciousness
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Mood altered (changes in mood)
Panic attack
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Red blood cell count decreased
Swelling
Thalamic infarction (tissue death of thalamus part of brain)
Tongue blistering

60+:

Confusional state
Memory impairment

What are the existing conditions these people have? *

High Blood Cholesterol: 2 people, 18.18%
Quit Smoking: 1 person, 9.09%
Diabetes: 1 person, 9.09%
Asthma: 1 person, 9.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 9.09%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 9.09%
Carcinoid Tumor: 1 person, 9.09%
Cardiac Disorder: 1 person, 9.09%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 9.09%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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