Lamotrigine and Benlysta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Benlysta (belimumab). Common drug interactions include fatigue among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Benlysta. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Benlysta?

Benlysta has active ingredients of belimumab. It is often used in systemic lupus erythematosus. eHealthMe is studying from 23,528 Benlysta users. Check the latest studies of Benlysta.

On Jul, 26, 2026

34 people who take Lamotrigine and Benlysta together, and have interactions are studied.

Lamotrigine and Benlysta drug interactions.

What are the common drug interactions of Lamotrigine and Benlysta, by gender? *:

female:

Fatigue (feeling of tiredness)
Headache (pain in head)
Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Rash
Diarrhoea
Alopecia (absence of hair from areas of the body)
Hypertension (high blood pressure)
Drug ineffective
Malaise (a feeling of general discomfort or uneasiness)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Oropharyngeal pain
Rhinorrhoea (watery mucus discharge from the nose)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Viral infection
Diarrhoea
Fatigue (feeling of tiredness)
Headache (pain in head)
Infusion site mass

What are the common drug interactions of Lamotrigine and Benlysta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cardiovascular disorder (heart diseases)
Cellulitis (infection under the skin)
Chills (felling of cold)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dizziness
Drug ineffective
Ear infection
Fall
Feeling cold

10-19:

Infection

20-29:

n/a

30-39:

Headache (pain in head)
Fatigue (feeling of tiredness)
Sinusitis (inflammation of sinus)
Surgery
Herpes zoster
Joint swelling
Migraine (headache)
Pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased

40-49:

Infusion site pain
Injection site pruritus (severe itching at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Myalgia (muscle pain)
Nephrolithiasis (calculi in the kidneys)
Oedema peripheral (superficial swelling)
Pruritus (severe itching of the skin)
Renal failure (kidney dysfunction)
Swelling face
Swollen tongue (swelling of tongue)

50-59:

Headache (pain in head)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Chills (felling of cold)
Chronic kidney disease
Dizziness
Head discomfort
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Influenza

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dyspnoea (difficult or laboured respiration)
Pneumonia
Surgery
Anxiety
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cough
Epistaxis (bleed from the nose)
Feeling jittery

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.82%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 8.82%
Drowsiness: 3 people, 8.82%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 5.88%
Insomnia (sleeplessness): 2 people, 5.88%
Immunodeficiency Common Variable: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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