Lamotrigine and Daptomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Daptomycin (daptomycin). Common drug interactions include pyrexia among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Daptomycin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.



On Jul, 26, 2026

22 people who take Lamotrigine and Daptomycin together, and have interactions are studied.

Lamotrigine and Daptomycin drug interactions.

What are the common drug interactions of Lamotrigine and Daptomycin, by gender? *:

female:

  1. Pyrexia (fever)
  2. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  3. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  4. Pancreatitis (inflammation of pancreas)
  5. Drug resistance (reduction in effectiveness of a drug)
  6. Neutropenia (an abnormally low number of neutrophils)
  7. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  8. Tendon rupture (tear of tendon)

male:

  1. Weight decreased
  2. Alanine aminotransferase increased
  3. Memory impairment
  4. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  5. Platelet count decreased
  6. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  7. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Skin infection
  10. Soft tissue infection

What are the common drug interactions of Lamotrigine and Daptomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Alanine aminotransferase increased
  2. Catheter site cellulitis (infection of cells near catheter)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Device dislocation
  5. Haematocrit decreased
  6. Haemoglobin decreased
  7. Infection
  8. Injection site pain
  9. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  10. Platelet count decreased

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  2. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  3. Pancreatitis (inflammation of pancreas)
  4. Drug resistance (reduction in effectiveness of a drug)
  5. Neutropenia (an abnormally low number of neutrophils)

60+:

  1. Pyrexia (fever)
  2. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  3. Essential tremor
  4. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  5. Speech disorder
  6. Tendon rupture (tear of tendon)

What are the existing conditions these people have? *

  1. Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 10 people, 45.45%
  2. Pain: 4 people, 18.18%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 18.18%
  4. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamotrigine and Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamotrigine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamotrigine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daptomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine and daptomycin (the active ingredients of Lamotrigine and Daptomycin, respectively), and Lamotrigine and Daptomycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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