Lamotrigine and Lenalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Lenalidomide (lenalidomide). Common drug interactions include general physical health deterioration among females and injection site reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Lenalidomide. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,639 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

31 people who take Lamotrigine and Lenalidomide together, and have interactions are studied.

Lamotrigine and Lenalidomide drug interactions.

What are the common drug interactions of Lamotrigine and Lenalidomide, by gender? *:

female:

General physical health deterioration (weak health status)
Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Thrombocytopenia (decrease of platelets in blood)
Headache (pain in head)
Chest pain
Depression
Diarrhoea
Dyspepsia (indigestion)
Insomnia (sleeplessness)

male:

Injection site reaction
Cellulitis (infection under the skin)
Peripheral swelling
Pyrexia (fever)
Rash
Sleep disorder
Tremor (trembling or shaking movements in one or more parts of your body)
Bacterial infection
Diarrhoea
Dysarthria (speech disorder)

What are the common drug interactions of Lamotrigine and Lenalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Allergic granulomatous angiitis (allergic inflammation of a blood vessel or lymph duct)
Chest pain
Depression
Dyspepsia (indigestion)
Headache (pain in head)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Night sweats (sweating in night)

50-59:

Diarrhoea
Chest pain
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Tooth disorder (tooth disease)
Vomiting

60+:

General physical health deterioration (weak health status)
Hyperkalaemia (damage to or disease of the kidney)
Chest pain
Chills (felling of cold)
Colitis (inflammation of colon)
Cough
Depression
Diarrhoea
Dysarthria (speech disorder)
Dyspepsia (indigestion)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 20 people, 64.52%
Oedema Peripheral (superficial swelling): 4 people, 12.90%
Depression: 4 people, 12.90%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 12.90%
Tinea Infection (fungal skin infection): 3 people, 9.68%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 9.68%
Diarrhea: 3 people, 9.68%
Iron Overload: 2 people, 6.45%
Fatigue (feeling of tiredness): 2 people, 6.45%
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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